American Journal of Obstetrics & Gynecology
Volume 202, Issue 6 , Pages 538.e1-538.e9 , June 2010

Prophylactic bilateral oophorectomy or removal of remaining ovary at the time of hysterectomy in the United States, 1979-2004

Presented orally at the 29th Scientific Meeting of the American Urogynecologic Society, Chicago, IL, Sept. 4-6, 2008.

  • Jerry L. Lowder, MD, MSc

      Affiliations

    • Division of Urogynecology, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Sallie S. Oliphant, MD

      Affiliations

    • Division of Urogynecology, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Chiara Ghetti, MD

      Affiliations

    • Division of Urogynecology, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Lara J. Burrows, MD, MSc

      Affiliations

    • Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, and the Center for Vulvovaginal Disorders, Washington, DC
    • ,
  • Leslie A. Meyn, MS

      Affiliations

    • Division of Obstetric and Gynecologic Infectious Disease, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA
    • ,
  • Judith Balk, MD

      Affiliations

    • Division of Gynecologic Specialties, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA

Received 29 May 2009 ,Revised 24 September 2009 ,Accepted 18 November 2009.

References 

  1. Whiteman MK, Hillis SD, Jamieson DJ, et al. Inpatient hysterectomy surveillance in the United States, 2000-2004. Am J Obstet Gynecol. 2008;198:34.e1–34.e7
  2. Keshavarz H, Hillis SD, Kiele BA, Marchbanks PA. Hysterectomy surveillance: United States, 1994-1999. MMWR Surveil Summ. 2002;51:1–8www.cdc.gov/MWR/preview/mmwrhtml/ss5105a1.htmAccessed April 1, 2009
  3. American Cancer Society. Cancer facts & figures 2008. www.cancer.org/downloads/STT/2008CAFFfinalsecured.pdfAccessed April 1, 2009
  4. Hankinson SE, Hunter DJ, Colditz GA, et al. Tubal ligation, hysterectomy, and risk of ovarian cancer: a prospective study. JAMA. 1993;270:2813–2818
  5. Utian WH, Goldfarb J. Ovarian management during radical hysterectomy in the premenopausal patient. Obstet Gynecol. 1993;82:1042
  6. Sightler SE, Boike GM, Estrape RE, Averette HE. Ovarian cancer in women with prior hysterectomy: a 14-year experience at the University of Miami. Obstet Gynecol. 1991;78:681–684
  7. Counseller VS, Hunt W, Haigler FH. Carcinoma of the ovary following hysterectomy. Am J Obstet Gynecol. 1955;69:538–546
  8. Parrazini F, Negri E, La Vecchia C, Luchini L, Mezzopane R. Hysterectomy, oophorectomy, and subsequent ovarian cancer risk. Obstet Gynecol. 1993;81:63–66
  9. Rocca WA, Grossardt BR, de Andrade M, Malkasian GD, Melton LJ. Survival patterns after oophorectomy in premenopausal women: a population-based cohort study. Lancet Oncol. 2006;7:821–828
  10. Parker WH, Broder MS, Chang E, et al. Ovarian conservation at the time of hysterectomy and long-term health outcomes in the Nurses' Health study. Obstet Gynecol. 2009;113:1027–1037
  11. Dennison C, Pokras R. Design and operation of the National Hospital Discharge Survey: 1988 redesign. Vital Health Stat. 2000;1:
  12. Jacoby VL, Vittinghoff E, Nakagawa S, et al. Factors associated with undergoing bilateral salpingo-oophorectomy at the time of hysterectomy for benign conditions. Obstet Gynecol. 2009;113:1259–1267
  13. Parker WH, Shoupe C, Broder MS, Liu Z, Farquhar C, Berek JS. Elective oophorectomy in the gynecological patient: when is it desirable?. Curr Opin Obstet Gynecol. 2007;19:350–354
  14. Hendrix SL. Bilateral oophorectomy and premature menopause. Am J Med. 2005;118:131S–135S
  15. Fogle RH, Stanczyk FZ, Zhang X, Paulson R. Ovarian androgen production in postmenopausal women. J Clin Endocrinol Metab. 2007;92:3040–3043
  16. Wuest J, Dry T, Edwards J. The degree of coronary atherosclerosis in bilaterally oophorectomized women. Circulation. 1953;7:801–809
  17. Kannel WB, Hjortland MC, McNamara PM, Gordon T. Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med. 1976;85:447–452
  18. Beard CM, Fuster V, Annegers JF. Reproductive history in women with coronary heart disease: the Framingham study. Am J Epidemiol. 1984;120:108–114
  19. Matthews KA, Meilahnm E, Kuller LH, et al. Menopause and risk factors of coronary heart disease. N Engl J Med. 1989;321:641–646
  20. Howard BV, Kuller L, Langer R, et al. Risk of cardiovascular disease by hysterectomy status, with and without oophorectomy: the Womens' Health Initiative observational study. Circulation. 2005;111:1462–1470
  21. Writing group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321–333
  22. Neron M. Deaths: leading causes for 2004. Natl Vital Stat Rep. 2007;56:1–96
  23. Cummings S, Browner W, Bauer D, et al. Endogenous hormones and the risk of hip and vertebral fractures among older women. N Engl J Med. 1998;339:733–738
  24. National Osteoporosis Foundation. Physician guide to prevention and treatment of osteoporosis. Beele Mead, NJ: Excerpta Medica, Inc; 1998;
  25. Melton LJ, Khosla S, Malkasian GD, Achenbach SJ, Oberg AL, Riggs BL. Fracture risk after bilateral oophorectomy in elderly women. J Bone Miner Res. 2003;18:900–905
  26. Parker WH, Broder MS, Liu Z, Shoupe D, Farquhar C, Berek JS. Ovarian conservation at the time of hysterectomy for benign disease. Obstet Gynecol. 2005;106:219–226
  27. Shoupe D, Parker WH, Broder MS, Liu Z, Farquhar C, Berek JS. Elective oophorectomy for benign gynecological disorders. Menopause. 2007;14:580–585
  28. Dekel A, Ewfrat Z, Orvieto R, et al. The residual ovary syndrome: a 20-year experience. Eur J Obstet Gynecol Reprod Biol. 1996;68:159–164
  29. Guay MP, Dragomir A, Pilon D, Moride Y, Perreault S. Changes in pattern of use, clinical characteristics and persistence rate of hormone replacement therapy among postmenopausal women after the WHI publication. Pharmacoepidemiol Drug Saf. 2007;16:17–27
  30. Lepine LA, Hillis SD, Marchbanks PA, et al. Hysterectomy surveillance: United States, 1980-1993. MMWR CDC Surveill Summ. 1997;46:1–15
  31. Jacobson GF, Shaber RE, Armstrong MA, Hung YY. Hysterectomy rates for benign conditions. Obstet Gynecol. 2006;107:1278–1283
  32. Farquhar CM, Steiner CA. Hysterectomy rates in the United States 1990-1997. Obstet Gynecol. 2002;99:229–234
  33. Whiteman MK, Hillis SD, Jamieson DJ, et al. Inpatient hysterectomy surveillance in the United States, 2000-2004. Am J Obstet Gynecol. 2008;198:34.e1–34.e7
  34. Morrison JE, Jacobs VR. Outpatient laparoscopic hysterectomy in a rural ambulatory surgery center. J Am Assoc Gynecol Laparosc. 2004;11:359–364
  35. Galen DI, Jacobson A, Weckstein LN. Outpatient laparoscopic-assisted vaginal hysterectomy. J Am Assoc Gynecol Laparosc. 1994;1:241–245
  36. National Ambulatory Surgical Survey. www.cdc.gov/nchs/products/elec_prods/subject/nsas.htmlApril 1, 2009
  37. Owings MF, Kozak LJ. Ambulatory and inpatient procedures in the United States, 1996. Vital Health Stat 13. 1998;139:1–119
  38. Hurskainen R, Teperi J, Rissanen P, et al. Clinical outcomes and costs with the levonorgestrel releasing intrauterine system or hysterectomy for treatment of menorrhagia: randomized trial 5-year follow-up. JAMA. 2004;291:1456–1463
  39. Fraquhar CM, Naoom S, Steiner CA. The impact of endometrial ablation on hysterectomy rates in women with benign uterine conditions in the United States. Int J Technol Assess Health Care. 2002;18:625–634
  40. The REST Investigators. Uterine-artery embolization versus surgery for symptomatic uterine fibroids. N Engl J Med. 2007;356:360–370
  41. Ballard LA, Walters MD. Transvaginal mobilization and removal of ovaries and fallopian tubes after vaginal hysterectomy. Obstet Gynecol. 1996;87:35–39

 Reprints not available from the authors.

 Cite this article as: Lowder JL, Oliphant SS, Ghetti C, et al. Prophylactic bilateral oophorectomy or removal of remaining ovary at the time of hysterectomy in the United States, 1979-2004. Am J Obstet Gynecol 2010;202:538.e1-9.

PII: S0002-9378(09)02204-2

doi: 10.1016/j.ajog.2009.11.030

American Journal of Obstetrics & Gynecology
Volume 202, Issue 6 , Pages 538.e1-538.e9 , June 2010

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