American Journal of Obstetrics & Gynecology
Volume 202, Issue 2 , Pages 155.e1-155.e4 , February 2010

Prediction of spontaneous preterm birth in asymptomatic twin pregnancies using the change in cervical length over time

Presented as a poster at the 29th Annual Meeting of the Society for Maternal-Fetal Medicine, San Diego, CA, Jan. 26-31, 2009.

  • Nathan S. Fox, MD

      Affiliations

    • Carnegie Hill Imaging for Women, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, NY
    • Corresponding Author InformationReprints: Nathan S. Fox, MD, Maternal Fetal Medicine Associates, PLLC, 70 E. 90 St., New York, NY 10128
    • ,
  • Andrei Rebarber, MD

      Affiliations

    • Carnegie Hill Imaging for Women, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, NY
    • ,
  • Chad K. Klauser, MD

      Affiliations

    • Carnegie Hill Imaging for Women, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, NY
    • ,
  • Danielle Peress, BS

      Affiliations

    • Carnegie Hill Imaging for Women, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, NY
    • ,
  • Christine V. Gutierrez, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Metropolitan Hospital Center, New York, NY
    • ,
  • Daniel H. Saltzman, MD

      Affiliations

    • Carnegie Hill Imaging for Women, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, NY

Received 22 May 2009 ,Revised 17 July 2009 ,Accepted 10 September 2009.

References 

  1. Martin JA, Kung HC, Mathews TJ, et al. Annual summary of vital statistics: 2006. Pediatrics. 2008;121:788–801
  2. Goldenberg RL, Iams JD, Miodovnik M, et al. The preterm prediction study: risk factors in twin gestations (National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network). Am J Obstet Gynecol. 1996;175:1047–1053
  3. Souka AP, Heath V, Flint S, Sevastopoulou I, Nicolaides KH. Cervical length at 23 weeks in twins in predicting spontaneous preterm delivery. Obstet Gynecol. 1999;94:450–454
  4. Imseis HM, Albert TA, Iams JD. Identifying twin gestations at low risk for preterm birth with a transvaginal ultrasonographic cervical measurement at 24 to 26 weeks' gestation. Am J Obstet Gynecol. 1997;177:1149–1155
  5. Guzman ER, Walters C, O'Reilly-Green C, et al. Use of cervical ultrasonography in prediction of spontaneous preterm birth in twin gestations. Am J Obstet Gynecol. 2000;183:1103–1107
  6. Naim A, Haberman S, Burgess T, Navizedeh N, Minkoff H. Changes in cervical length and the risk of preterm labor. Am J Obstet Gynecol. 2002;186:887–889
  7. Fox NS, Jean-Pierre C, Predanic M, Chasen ST. Short cervix: is a follow-up measurement useful?. Ultrasound Obstet Gynecol. 2007;29:44–46
  8. Bergelin I, Valentin L. Cervical changes in twin pregnancies observed by transvaginal ultrasound during the latter half of pregnancy: a longitudinal, observational study. Ultrasound Obstet Gynecol. 2003;21:556–563
  9. Gibson JL, Macara LM, Owen P, Young D, Macauley J, Mackenzie F. Prediction of preterm delivery in twin pregnancy: a prospective, observational study of cervical length and fetal fibronectin testing. Ultrasound Obstet Gynecol. 2004;23:561–566
  10. Iams JD, Goldenberg RL, Meis PJ, et al. The length of the cervix and the risk of spontaneous preterm delivery. N Engl J Med. 1996;334:567–572
  11. Yost NP, Bloom SL, Twickler DM, Levano KJ. Pitfalls in ultrasound cervical length measurements for predicting preterm birth. Obstet Gynecol. 1999;93:510–516
  12. Martin JA, Hamilton BE, Sutton PD, et al. Births: final data for 2005. Natl Vital Stat Rep. 2007;56:1–103
  13. National Center for Health Statistics. Final natality data. http://www.marchofdimes.com/peristatsAccessed Oct. 29, 2008
  14. Berghella V, Odibo AO, To MS, Rust OA, Althuisius SM. Cerclage for short cervix on ultrasonography: meta-analysis of trials using individual patient-level data. Obstet Gynecol. 2005;106:181–189
  15. Crowther CA. Hospitalization and bed rest for multiple pregnancy. Cochrane Database Syst Rev. 2001;1:CD000110
  16. Rouse DJ, Caritis SN, Peaceman AM, et al. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network A trial of 17 alpha-hydroxyprogesterone caproate to prevent prematurity in twins. N Engl J Med. 2007;357:454–461
  17. Fonseca EB, Celik E, Parra M, Singh M, Nicolaides KH Fetal Medicine Foundation Second Trimester Screening Group. Progesterone and the risk of preterm birth among women with a short cervix. N Engl J Med. 2007;357:462–469
  18. Morgan MA, Goldenberg RL, Schulkin J. Obstetrician-gynecologists' screening and management of preterm birth. Obstet Gynecol. 2008;112:35–41

 Cite this article as: Fox NS, Rebarber A, Klauser CK, et al. Prediction of spontaneous preterm birth in asymptomatic twin pregnancies using the change in cervical length over time. Am J Obstet Gynecol 2010;202:155.e1-4.

PII: S0002-9378(09)01011-4

doi: 10.1016/j.ajog.2009.09.004

American Journal of Obstetrics & Gynecology
Volume 202, Issue 2 , Pages 155.e1-155.e4 , February 2010

Article Tools