American Journal of Obstetrics & Gynecology
Volume 202, Issue 1 , Pages 15-29, January 2010

Current diagnosis and treatment of interstitial pregnancy

  • Nash S. Moawad, MD

      Affiliations

    • Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA
    • Corresponding Author InformationReprints: Nash S. Moawad, MD, 300 Halket St., Pittsburgh, PA 15213
    • ,
  • Sangeeta T. Mahajan, MD

      Affiliations

    • Department of Obstetrics, Gynecology and Reproductive Biology, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, Ohio
    • ,
  • Michelle H. Moniz, MD

      Affiliations

    • Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA
    • ,
  • Sarah E. Taylor, MD

      Affiliations

    • Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA
    • ,
  • William W. Hurd, MD, MSc

      Affiliations

    • Department of Obstetrics, Gynecology and Reproductive Biology, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, Ohio

Received 17 May 2009; received in revised form 4 July 2009; accepted 20 July 2009.

The incidence of interstitial pregnancy is rising. Traditional treatment with laparotomy, hysterectomy, or cornual wedge resection is associated with high morbidity and detrimental effects on future fertility. A diverse array of alternate treatments has been introduced over the last 3 decades, with the common goal of achieving a minimally invasive, standardized management strategy. This has been facilitated by impressive strides towards prompt diagnosis, both radiologically and chemically. In this review, we explore the current state of the art diagnostic criteria and the clinically significant diverse therapeutic options with supporting literature. Finally, we propose a structured, best-practice management plan for the once-lethal interstitial pregnancy, based on the current literature.

Key words: interstitial pregnancy, cornual, ectopic, laparoscopic treatment

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 Authorship and contribution to the article is limited to the 5 authors indicated. There was no outside funding or technical assistance with the production of this article.

PII: S0002-9378(09)00840-0

doi:10.1016/j.ajog.2009.07.054

American Journal of Obstetrics & Gynecology
Volume 202, Issue 1 , Pages 15-29, January 2010

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