American Journal of Obstetrics & Gynecology
Volume 201, Issue 5 , Pages 519.e1-519.e8 , November 2009

Anatomic outcomes of vaginal mesh procedure (Prolift) compared with uterosacral ligament suspension and abdominal sacrocolpopexy for pelvic organ prolapse: a Fellows' Pelvic Research Network study

Presented at the 35th Annual Meeting of the Society of Gynecologic Surgeons, New Orleans, LA, March 30-April 1, 2009.

  • Tatiana V.D. Sanses, MD

      Affiliations

    • Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Maryland Medical Center, and the Department of Gynecology, Female Urology, and Pelvic Surgery, Greater Baltimore Medical Center, Baltimore, MD
    • ,
  • Azin Shahryarinejad, MD, MPH

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, NY
    • ,
  • Stephanie Molden, MD

      Affiliations

    • Division of Urogynecology, Department of Obstetrics and Gynecology, St Luke's Hospital and Health Network, and The Institute for Female Pelvic Medicine and Reconstructive Surgery, Allentown, PA
    • ,
  • Kay A. Hoskey, MD

      Affiliations

    • Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Maryland Medical Center, and the Department of Gynecology, Female Urology, and Pelvic Surgery, Greater Baltimore Medical Center, Baltimore, MD
    • ,
  • Shameem Abbasy, MD, MPH

      Affiliations

    • Department of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, IL
    • ,
  • Danielle Patterson, MD

      Affiliations

    • Division of Urogynecology, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA
    • ,
  • Emily K. Saks, MD

      Affiliations

    • Division of Urogynecology, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA
    • ,
  • Emily E. Weber LeBrun, MD

      Affiliations

    • Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Massachusetts Memorial Medical Center, Worcester, MA
    • ,
  • Tondalaya L. Gamble, MD

      Affiliations

    • Evanston Continence Center and the Division of Urogynecology, Department of Obstetrics and Gynecology, Evanston Northshore University HealthSystem, Northwestern University, Evanston, IL
    • ,
  • Virginia G. King, MD

      Affiliations

    • Division of Urogynecology and Reconstructive Pelvic Medicine, Department of Obstetrics and Gynecology, Oregon Health and Sciences University, Portland, OR
    • ,
  • Aimee L. Nguyen, MD

      Affiliations

    • Evanston Continence Center and the Division of Urogynecology, Department of Obstetrics and Gynecology, Evanston Northshore University HealthSystem, Northwestern University, Evanston, IL
    • ,
  • Husam Abed, MD

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Henry Ford Health System, Detroit, MI
    • ,
  • Stephen B. Young, MD

      Affiliations

    • Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Massachusetts Memorial Medical Center, Worcester, MA
    • ,
  • Fellows' Pelvic Research Network

Received 30 December 2008 ,Revised 30 May 2009 ,Accepted 1 July 2009.

References 

  1. Dallenbach P, Kaelin-Gambirasio I, Jacob S, Dubuisson JB, Boulvain M. Incidence rate and risk factors for vaginal vault prolapse repair after hysterectomy. Int Urogynecol J Pelvic Floor Dysfunct. 2008;19:1623–1629
  2. Kenton K, Sadowski D, Shott S, Brubaker L. A comparison of women with primary and recurrent pelvic prolapse. Am J Obstet Gynecol. 1999;180:1415–1418
  3. Olsen Al, Smith VJ, Bergstrom JO, Colling JC, Clark AL. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol. 1997;89:501–506
  4. Kenton K, Mueller E. Surgical repair of the middle compartment. Clin Obstet Gynecol. 2005;48:691–703
  5. Novara G, Galfano A, Secco S, Ficarra V, Artibani W. Prolapse surgery: an update. Curr Opin Urol. 2007;17:237–241
  6. Barber MD, Visco AG, Weidner AC, Amundsen CL, Bump RC. Bilateral uterosacral ligament vaginal vault suspension with site-specific endopelvic fascia defect repair for treatment of pelvic organ prolapse. Am J Obstet Gynecol. 2000;183:1402–1410discussion 1410-1
  7. Karram M, Goldwasser S, Kleeman S, Steele A, Vassallo B, Walsh P. High uterosacral vaginal vault suspension with fascial reconstruction for vaginal repair of enterocele and vaginal vault prolapse. Am J Obstet Gynecol. 2001;185:1339–1342discussion 1342-3
  8. Shull BL, Bachofen C, Coates KW, Kuehl TJ. A transvaginal approach to repair of apical and other associated sites of pelvic organ prolapse with uterosacral ligaments. Am J Obstet Gynecol. 2000;183:1365–1373discussion 1373-4
  9. Silva WA, Pauls RN, Segal JL, Rooney CM, Kleeman SD, Karram MM. Uterosacral ligament vault suspension: five-year outcomes. Obstet Gynecol. 2006;108:255–263
  10. Wheeler TL, Gerten KA, Richter HE, Duke AG, Varner RE. Outcomes of vaginal vault prolapse repair with a high uterosacral suspension procedure utilizing bilateral single sutures. Int Urogynecol J Pelvic Floor Dysfunct. 2007;18:1207–1213
  11. Benson JT, Lucente V, McClellan E. Vaginal versus abdominal reconstructive surgery for the treatment of pelvic support defects: a prospective randomized study with long-term outcome evaluation. Am J Obstet Gynecol. 1996;175:1418–1421discussion 1421-2
  12. Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S. Surgical management of pelvic organ prolapse in women. Cochrane Database Syst Rev. 2004;CD004014
  13. Nygaard IE, Mccreery R, Brubaker L, et al. Abdominal sacrocolpopexy: a comprehensive review. Obstet Gynecol. 2004;104:805–823
  14. Caquant F, Collinet P, Debodinance P, et al. Safety of trans vaginal mesh procedure: retrospective study of 684 patients. J Obstet Gynaecol Res. 2008;34:449–456
  15. De Tayrac R, Deffieux X, Gervaise A, Chauveaud-Lambling A, Fernandez H. Long-term anatomical and functional assessment of trans-vaginal cystocele repair using a tension-free polypropylene mesh. Int Urogynecol J Pelvic Floor Dysfunct. 2006;17:483–488
  16. De Tayrac R, Gervaise A, Chauveaud A, Fernandez H. Tension-free polypropylene mesh for vaginal repair of anterior vaginal wall prolapse. J Reprod Med. 2005;50:75–80
  17. Debodinance P, Amblard J, Fatton B, Cosson M, Jacquetin B. [The prosthetic kits in the prolapse surgery: is it a gadget. J Gynecol Obstet Biol Reprod (Paris). 2007;36:267–275
  18. Debodinance P, Cosson M, Collinet P, Boukerrou M, Lucot JP, Madi N. Synthetic meshes for transvaginal surgical cure of genital prolapse: evaluation in 2005. J Gynecol Obstet Biol Reprod (Paris). 2006;35:429–454
  19. Hinoul P, Ombelet WU, Burger MP, Roovers JP. A prospective study to evaluate the anatomic and functional outcome of a transobturator mesh kit (prolift anterior) for symptomatic cystocele repair. J Minim Invasive Gynecol. 2008;15:615–620
  20. FDA med watch page. Food and Drug Administration web site. http://www.fda.gov/medwatch/safety/2008/safety08.htm#meshAccessed Nov. 6, 2008
  21. Murphy M. Clinical practice guidelines on vaginal graft use from the society of gynecologic surgeons. Obstet Gynecol. 2008;112:1123–1130
  22. Bump RC, Mattiasson A, Bo K, et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol. 1996;175:10–17
  23. Baden WF, Walker TA, Lindsey JH. The vaginal profile. Tex Med. 1968;64:56–58
  24. Baden W, Walker T. Surgical repair of vaginal defects. Philadelphia, PA: J. B. Lippincott; 1992;
  25. Prolift [package insert]. Prolift Gynecare/Ethicon, Somerville, NJ. Available at: http://www.jnjgateway.com/public/GBENG/PROLIFT_EPI.pdf. Accessed Dec. 5, 2008.
  26. Cosson M, Caquant F, Collinet P, et al. Prolift mesh (Gynecare) for pelvic organ prolapse surgical treatment using the TVM group technique: a retrospective study of 687 patients. Neurourol Urodyn. 2005;2:590–592
  27. Cosson M, Rosenthal C, Clave H, et al. Prospective clinical assessment of the total transvaginal mesh (TVM) technique for treatment of pelvic organ prolapse—6 and 12 month results. Int Urogynecol J. 2006;17:S142
  28. Van Raalte HM, Lucente VR, Molden SM, Haff R, Murphy M. One-year anatomic and quality-of-life outcomes after the Prolift procedure for treatment of posthysterectomy prolapse. Am J Obstet Gynecol. 2008;199:694.e1–694.e6
  29. Alperin M, Sutkin G, Ellison R, Meyn L, Moalli P, Zyczynki H. Peri-operative outcomes of the Prolift pelvic floor repair systems following introduction to a urogynecology teaching service. Int Urogynecol J Pelvic Floor Dysfunct. 2008;19:1617–1622
  30. Altman D, Vayrynen T, Engh Me, Axelsen S, Falconer C. Short-term outcome after transvaginal mesh repair of pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct. 2008;19:787–793

 Cite this article as: Sanses TVD, Shahryarinejad A, Molden S, et al. Anatomic outcomes of vaginal mesh procedure (Prolift) compared with uterosacral ligament suspension and abdominal sacrocolpopexy for pelvic organ prolapse: a Fellows' Pelvic Research Network study. Am J Obstet Gynecol 2009;201:519.e1-8.

 Reprints not available from the authors.

 The Fellows' Pelvic Research Network is sponsored by the Society of Gynecologic Surgeons.

PII: S0002-9378(09)00770-4

doi: 10.1016/j.ajog.2009.07.004

American Journal of Obstetrics & Gynecology
Volume 201, Issue 5 , Pages 519.e1-519.e8 , November 2009

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