American Journal of Obstetrics & Gynecology
Volume 201, Issue 6 , Pages 574.e1-574.e5, December 2009

Intravenous leiomyomatosis with intracardiac extension: a single-institution experience

  • Micheal J. Worley Jr, MD

      Affiliations

    • Department of Obstetrics and Gynecology, New York Presbyterian Hospital–Weill-Cornell Medical College, New York, NY
    • ,
  • Anate Aelion, MD

      Affiliations

    • Department of Obstetrics and Gynecology, New York Presbyterian Hospital–Weill-Cornell Medical College, New York, NY
    • ,
  • Thomas A. Caputo, MD

      Affiliations

    • Department of Gynecologic Oncology, New York Presbyterian Hospital–Weill Cornell Medical College, New York, NY
    • ,
  • Kenneth C. Kent, MD

      Affiliations

    • Division of Vascular Surgery, New York Presbyterian Hospital–Weill Cornell Medical College, New York, NY
    • ,
  • Arash Salemi, MD

      Affiliations

    • Division of Cardiovascular Surgery, New York Presbyterian Hospital–Weill Cornell Medical College, New York, NY
    • ,
  • Karl H. Krieger, MD

      Affiliations

    • Division of Cardiovascular Surgery, New York Presbyterian Hospital–Weill Cornell Medical College, New York, NY
    • ,
  • Michael J. Goldstein, MD

      Affiliations

    • Department of Surgery, New York Presbyterian Hospital–Weill Cornell Medical College, New York, NY
    • Center for Liver Disease and Transplantation, New York Presbyterian Hospital, Columbia University, New York, NY
    • ,
  • Dennis Y. Kuo, MD

      Affiliations

    • Department of Obstetrics and Gynecology, New York Presbyterian Hospital–Weill-Cornell Medical College, New York, NY
    • ,
  • Brian M. Slomovitz, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Women's Cancer Center, Morristown Memorial Hospital, Morristown, NJ

Received 21 April 2009; received in revised form 10 May 2009; accepted 12 June 2009. published online 03 September 2009.

Objective

The aim of this study was to outline the surgical management and outcomes for patients diagnosed with intravenous leiomyomatosis with intracardiac extension at a single institution.

Study Design

This was a retrospective review of patients diagnosed with intravenous leiomyomatosis with intracardiac extension between 2002–2008.

Results

Four patients were identified. The surgical approach in 3 (75%) patients was a single-stage operation. Four (100%) patients presented with cardiac symptoms: 3 (75%) with syncope and 1 (25%) with an abnormal electrocardiogram. Mean age at presentation was 48 years (range, 42–58 years). Complete resection of tumor was obtained in 1 (25%) patient and 3 (75%) patients experienced incomplete resection. Mean follow-up, including surveillance imaging, was 25.5 months (range, 8–57 months) and all 4 patients (100%) are currently free of recurrence.

Conclusion

Surgical excision remains an effective therapy for treating patients with benign metastasizing leiomyomatosis. Incomplete surgical resection may result in favorable response.

Key words: cardiac mass, fibroid, intravenous leiomyomatosis

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 Reprints not available from the authors.

 Film footage of the surgical procedure described in this article has been used to create a video abstract and was presented at the 57th Annual Clinical Meeting of the American College of Obstetricians and Gynecologists, Chicago, IL, May 2-6, 2009.

 Cite this article as: Worley MJ Jr, Aelion A, Caputo TA, et al. Intravenous leiomyomatosis with intracardiac extension: a single-institution experience. Am J Obstet Gynecol 2009;201:574.e1-5.

PII: S0002-9378(09)00681-4

doi:10.1016/j.ajog.2009.06.037

American Journal of Obstetrics & Gynecology
Volume 201, Issue 6 , Pages 574.e1-574.e5, December 2009

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