American Journal of Obstetrics & Gynecology
Volume 201, Issue 1 , Pages 5-11 , July 2009

The role of transvaginal ultrasound or endometrial biopsy in the evaluation of the menopausal endometrium

Received 4 August 2008 ,Revised 22 January 2009 ,Accepted 18 February 2009.

References 

  1. Nasri MN, Coast GJ. Correlation of ultrasound findings and endometrial histopathology in postmenopausal women. Br J Obstet Gynaecol. 1989;96:1333–1338
  2. Goldstein SR, Nachtigall M, Snyder JR, Nachtigall L. Endometrial assessment by vaginal ultrasonography before endometrial sampling in patients with postmenopausal bleeding. Am J Obstet Gynecol. 1990;163:119–123
  3. Varner RE, Sparks JM, Cameron CD, et al. Transvaginal sonography of the endometrium in postmenopausal women. Obstet Gynecol. 1991;78:195
  4. American Cancer Society. What are the key statistics about endometrial cancer?. http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_are_the_key_statistics_for_endometrial_cancer.asp?sitearea=Accessed July 16, 2008
  5. Goldstein RB, Bree RL, Benson CB, et al. Evaluation of the woman with postmenopausal bleeding: Society of Radiologists in Ultrasound–sponsored consensus conference statement. J Ultrasound Med. 2001;10:1025–1036
  6. Smith-Bindman R, Kerlikowske K, Feldstein V, et al. Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA. 1998;280:1510–1517
  7. Tabor A, Watt HC, Wald NJ. Endometrial thickness as a test for endometrial cancer in women with postmenopausal vaginal bleeding. Obstet Gynecol. 2002;99:663–670
  8. Gupta JK, Chien PF, Voit D, et al. Ultrasonographic endometrial thickness for diagnosing endometrial pathology in women with postmenopausal bleeding: a meta-analysis. Acta Obstet Gynecol Scand. 2002;81:799–816
  9. Smith-Bindman R, Weiss E, Feldtsein V. How thick is too thick? (When endometrial thickness should prompt biopsy in postmenopausal women without vaginal bleeding). Ultrasound Obstet Gynecol. 2004;24:558–565
  10. American College of Obstetrician and Gynecologists practice bulletin no. 14. March 2000. Management of anovulatory bleeding. Int J Gynaecol Obstet 2001;72:263-71.
  11. Goldstein SR. Sonohysterography. In: Ultrasound in gynecology. 2nd ed.. Philadelphia: Churchill Livingstone Inc; 1995;p. 209–210
  12. Ricci JV. Gynecologic surgery and instruments of the nineteenth century prior to the antiseptic age. In: The development of gynecological surgery and instruments. Philadelphia: Blakiston; 1949;p. 326–328
  13. Word B, Gravlee LC, Widemon GL. The fallacy of simple uterine curettage. Obstet Gynecol. 1958;12:642–645
  14. Stock RJ, Kanbour A. Prehysteroctomy curettage. Obstet Gynecol. 1975;45:537–541
  15. Vuopala S. Diagnostic accuracy and clinical applicability of cytological and histological methods for investigating endometrial carcinoma. Acta Obstet Gynecol Scand Suppl. 1997;70:1
  16. Kaunitz AM, Masciello AS, Ostrowsky M, Rovvira EZ. Comparison of endometrial Pipelle and Vabra aspirator. J Reprod Med. 1988;33:427–431
  17. Cornier E. The Pipelle: a disposable device for endometrial biopsy. Am J Obstet Gynecol. 1984;48:109–110
  18. Stovall TG, Photopulos GJ, Poston WM, Ling FW, Sandlers LG. Pipelle endometrial sampling in patients with known endometrial carcinoma. Obstet Gynecol. 1991;77:954–956
  19. Rodriguez MJ, Platt LD, Medearis AL, Lacarra M, Lobo RA. The use of transvaginal sonography for evaluation of postmenopausal size and morphology. Am J Obstet Gynecol. 1988;159:810–814
  20. Zorlu CG, Cobanoglu O, Isik AZ, Kutluay L, Kuscu E. Accuracy of Pipelle endometrial sampling in endometrial carcinoma. Gynecol Obstet Invest. 1994;38:272–275
  21. Ferry J, Farnsworth A, Webster M, Wren B. The efficacy of the Pipelle endometrial biopsy in detecting endometrial carcinoma. Aust N Z J Obstet Gynecol. 1993;33:76–78
  22. Guido RS, Kanbour-Shakir A, Rulin MC, Christopherson WA. Pipelle endometrial sampling (Sensitivity in the detection of endometrial cancer). J Reprod Med. 1995;40:553–555
  23. Goldchmit R, Katz A, Blickstein I, et al. The accuracy of endometrial Pipelle sampling with and without sonographic measurement of endometrial thickness. Obstet Gynecol. 1993;82:727–730
  24. Larson DM, Krawisz BR, Johnson KK, Broste SK. Comparison of the Z-sampler and Novak endometrial biopsy instruments for in-office diagnosis of endometrial cancer. Gynecol Oncol. 1994;54:64–67
  25. Granberg S, Wikland M, Karlsson B, et al. Endometrial thickness as measured by endovaginal ultrasonography for identifying endometrial abnormality. Am J Obstet Gynecol. 1991;164:47–52
  26. Karlsson B, Granberg S, Wikland M, et al. Transvaginal ultrasonography of the endometrium in women with postmenopausal bleeding–Nordic multicenter study. Am J Obstet Gynecol. 1995;172:1488–1494
  27. Ferrazzi E, Torri V, Trio D, Zannoni E, Filiberto S, Dordoni D. Sonographic endometrial thickness: a useful test to predict atrophy in patients with postmenopausal bleeding: an Italian multicenter study. Ultrasound Obstet Gynecol. 1996;7:315–321
  28. Gull B, Carlsson S, Karlsson B, Ylostalo P, Milsom I, Granberg S. Transvaginal ultrasonography of the endometrium in women with postmenopausal bleeding: is it always necessary to perform an endometrial biopsy?. Am J Obstet Gynecol. 2000;182:509–515
  29. Epstein E, Valentin L. Rebleeding and endometrial growth in women with postmenopausal bleeding and endometrial thickness < 5 mm managed by dilatation and curettage or ultrasound follow-up: a randomized controlled study. Ultrasound Obstet Gynecol. 2001;l8:499–504
  30. Gull B, Karlsson B, Milsom I, Granberg S. Can ultrasound replace dilatation and curettage? (A longitudinal evaluation of postmenopausal bleeding and transvaginal sonographic measurement of the endometrium as predictors of endometrial cancer). Am J Obstet Gynecol. 2003;188:401–408
  31. Elsandabesee D, Greenwood P. The performance of Pipelle endometrial sampling in a dedicated postmenopausal bleeding clinic. J Obstet Gynecol. 2005;25:32–34
  32. Dijkhuizen FP, Mol BW, Brolmann HA, Heintz AP. The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia: a meta-analysis. Cancer. 2000;89:1765–1772
  33. Goldstein SR. The endometrial echo revisited: have we created a monster?. Am J Obstet Gynecol. 2004;191:1092–1096
  34. Goldstein SR. Use of ultrasonohysterography for triage of perimenopausal patients with unexplained uterine bleeding. Am J Obstet Gynecol. 1994;170:565–570
  35. Barber H, Graber E. The PMPO syndrome (postmenopausal palpable ovary syndrome). Obstet Gynecol. 1971;38:921–923
  36. Hall DA, McCarthy KA. The significance of the postmenopausal simple adnexal cyst. J Ultrasound Med. 1986;5:503–505
  37. Goldstein SR, Subramanyam B, Snyder JR, Beller U, Raghavendra BN, Beckman EM. The postmenopausal cystic adnexal mass: the potential role of ultrasound in conservative management. Obstet Gynecol. 1989;73:8–10
  38. Goldstein SR. Postmenopausal adnexal cysts: how clinical management has evolved. Am J Obstet Gynecol. 1996;175:1498–1501
  39. Wolf SI, Gosink BB, Feldesman MR, et al. Prevalence of simple adnexal cysts in postmenopausal women. Radiology. 1991;180:65–71
  40. Berliere M, Radikov G, Galant C, Piette P, Marbaix E, Donnez J. Identification of women at high risk of developing endometrial cancer on tamoxifen. Eur J Cancer. 2000;6:S35–S36
  41. Clevenger-Hoeft M, Syrop CH, Stovall DW, Van Voorhis BJ. Sonohysterography in premenopausal women with and without abnormal bleeding. Obstet Gynecol. 1999;94:516–520
  42. Fay TN, Khanem N, Hosking D. Out-patient hysteroscopy in asymptomatic women. Climateric. 1999;2:263–267
  43. Fernandez-Parra J, Rodriguez Oliver A, Lopez Criado S, Parrilla Fernandez F, Montoya Ventoso F. Hysteroscopic evaluation of endometrial polyps. Int J Gynaecol Obstet. 2006;95:144–148
  44. Shushan A, Revel A, Rojansky N. How often are endometrial polyps malignant?. Gynecol Obstet Invest. 2004;58:212–215
  45. Lieng M, Qvigstad E, Sandvik L, Jorgensen H, Langebrekke A, Istre O. Hysteroscopic resection of symptomatic and asymptomatic endometrial polyps. J Minim Invasive Gynecol. 2007;14:189–194
  46. Lev-Sagie A, Hamani Y, Imbar T, Hurwitz A, Lavy Y. The significance of intrauterine lesions detected by ultrasound in asymptomatic postmenopausal patients. BJOG. 2005;112:379–381

 Reprints not available from the author.

PII: S0002-9378(09)00191-4

doi: 10.1016/j.ajog.2009.02.006

American Journal of Obstetrics & Gynecology
Volume 201, Issue 1 , Pages 5-11 , July 2009

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