American Journal of Obstetrics & Gynecology
Volume 199, Issue 6, Supplement B , Pages S345-S356 , December 2008

The clinical content of preconception care: nutrition and dietary supplements

  • Paula M. Gardiner, MD, MPH

      Affiliations

    • Department of Family Medicine, Boston University School of Medicine, Boston, MA
    • Corresponding Author InformationReprints: Paula Gardiner, MD, MPH, Boston Medical Center, 1 Boston Medical Center Place, Dowling 5 South, Boston, MA 02118
  • ,
  • Lauren Nelson

      Affiliations

    • Department of Family Medicine, Boston University School of Medicine, Boston, MA
  • ,
  • Cynthia S. Shellhaas, MD, MPH

      Affiliations

    • Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH
  • ,
  • Anne L. Dunlop, MD

      Affiliations

    • Department of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, GA
  • ,
  • Richard Long, MD

      Affiliations

    • Department of Family Medicine, Boston University School of Medicine, Boston, MA
  • ,
  • Sara Andrist, MPH, RD, LD

      Affiliations

    • Nutrition Section, Georgia Division of Public Health, Atlanta, GA
  • ,
  • Brian W. Jack, MD

      Affiliations

    • Department of Family Medicine, Boston University School of Medicine, Boston, MA

Received 17 June 2008 ,Revised 16 October 2008 ,Accepted 17 October 2008.

References 

  1. Fowles ER. What's a pregnant woman to eat? (A review of current USDA dietary guidelines and MyPyramid). J Perinat Educ. 2006;15:28–33
  2. Wu G, Bazer FW, Cudd TA, Meininger CJ, Spencer TE. Maternal nutrition and fetal development. J Nutr. 2004;134:2169–2172
  3. Williamson CS. Nutrition in pregnancy. Nutrition bulletin. 2006;31:28–59(96 references)
  4. Fall C. Fetal and maternal nutrition (The report of a British nutrition foundation task force). In: Cardiovascular disease: diet, nutrition and emerging risk factors. Oxford, UK: Blackwell Science; 2005;
  5. Godfrey KM, Barker DJ. Fetal nutrition and adult disease. Am J Clin Nutr. 2000;71:1344–1352
  6. Keen CL, Clegg MS, Hanna LA, et al. The plausibility of micronutrient deficiencies being a significant contributing factor to the occurrence of pregnancy complications. J Nutr. 2003;133:1597S–1605S
  7. Kaiser LL, Allen L. Position of the American Dietetic Association: nutrition and lifestyle for a healthy pregnancy outcome. J Am Diet Assoc. 2008;108:553–561
  8. Gunderson EP. Nutrition during pregnancy for the physically active woman. Clin Obstet Gynecol. 2003;46:390–402
  9. Glenville M. Nutritional supplements in pregnancy: commercial push or evidence based?. Curr Opin Obstet Gynecol. 2006;18:642–647
  10. Mehta SH. Nutrition and pregnancy. Clin Obstet Gynecol. 2008;51:409–418
  11. Cena ER, Joy AB, Heneman K, et al. Folate intake and food-related behaviors in nonpregnant, low-income women of childbearing age. J Am Diet Assoc. 2008;108:1364–1368
  12. Yang QH, Carter HK, Mulinare J, Berry RJ, Friedman JM, Erickson JD. Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: findings from the National Health and Nutrition Examination Survey, 2001-2002. Am J Clin Nutr. 2007;85:1409–1416
  13. de Weerd S, Steegers EA, Heinen MM, van den Eertwegh S, Vehof RM, Steegers-Theunissen RP. Preconception nutritional intake and lifestyle factors: first results of an explorative study. Eur J Obstet Gynecol Reprod Biol. 2003;111:167–172
  14. Cuco G, Arija V, Iranzo R, Vila J, Prieto MT, Fernandez-Ballart J. Association of maternal protein intake before conception and throughout pregnancy with birth weight. Acta Obstet Gynecol Scand. 2006;85:413–421
  15. Vujkovic M, Ocke MC, van der Spek PJ, Yazdanpanah N, Steegers EA, Steegers-Theunissen RP. Maternal Western dietary patterns and the risk of developing a cleft lip with or without a cleft palate. Obstet Gynecol. 2007;110:378–384
  16. Krapels IP, van Rooij IA, Ocke MC, West CE, van der Horst CM, Steegers-Theunissen RP. Maternal nutritional status and the risk for orofacial cleft offspring in humans. J Nutr. 2004;134:3106–3113
  17. Ross MP, Brundage S. Preconception counseling about nutrition and exercise. J S C Med Assoc. 2002;98:260–263
  18. Korenbrot CC, Steinberg A, Bender C, Newberry S. Preconception care: a systematic review. Matern Child Health J. 2002;6:75–88
  19. Ministry of Health. Food and nutrition guidelines for healthy pregnant and breastfeeding women: a background paper. Wellington, New Zealand: Ministry of Health; 2006;
  20. Institute of Medicine. Nutrition during pregnancy and lactation: an implementation guide. Washington (DC): The National Academies Press; 1992;
  21. Kennedy E, Meyers L. Dietary reference intakes: development and uses for assessment of micronutrient status of women—a global perspective. Am J Clin Nutr. 2005;81(Suppl):1194S–1197S(18 references)
  22. US Department of Health and Human Services and US Department of Agriculture. Dietary guidelines for Americans. Washington, DC: US Government Printing Office; 2005;
  23. van Breemen RB, Fong HH, Farnsworth NR. Ensuring the safety of botanical dietary supplements. Am J Clin Nutr. 2008;87:509S–513S
  24. Radimer K, Bindewald B, Hughes J, Ervin B, Swanson C, Picciano MF. Dietary supplement use by US adults: data from the National Health and Nutrition Examination Survey, 1999-2000. Am J Epidemiol. 2004;160:339–349
  25. Kelly JP, Kaufman DW, Kelley K, Rosenberg L, Anderson TE, Mitchell AA. Recent trends in use of herbal and other natural products. Arch Intern Med. 2005;165:281–286
  26. Gardiner P, Graham RE, Legedza A, Eisenberg DM, Phillips RS. Factors associated with dietary supplement use among prescription medication users. Arch Intern Med. 2006;166:1968–1974
  27. Tsui B, Dennehy CE, Tsourounis C. A survey of dietary supplement use during pregnancy at an academic medical center. Am J Obstet Gynecol. 2001;185:433–437
  28. Nordeng H, Havnen GC. Impact of socio-demographic factors, knowledge and attitude on the use of herbal drugs in pregnancy. Acta Obstet Gynecol Scand. 2005;84:26–33
  29. Zaffani S, Cuzzolin L, Benoni G. Herbal products: behaviors and beliefs among Italian women. Pharmacoepidemiol Drug Saf. 2006;15:354–359
  30. Howell L, Kochhar K, Saywell R, et al. Use of herbal remedies by Hispanic patients: do they inform their physician?. J Am Board Fam Med. 2006;19:566–578
  31. Gardiner P, Graham R, Legedza AT, Ahn AC, Eisenberg DM, Phillips RS. Factors associated with herbal therapy use by adults in the United States. Altern Ther Health Med. 2007;13:22–29
  32. Murphy SP, Wilkens LR, Hankin JH, et al. Comparison of two instruments for quantifying intake of vitamin and mineral supplements: a brief questionnaire versus three 24-hour recalls. Am J Epidemiol. 2002;156:669–675
  33. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai. 2007;90:15–20
  34. Borrelli F, Capasso R, Aviello G, Pittler MH, Izzo AA. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol. 2005;105:849–856
  35. Fugh-Berman A, Kronenberg F. Complementary and alternative medicine (CAM) in reproductive-age women: a review of randomized controlled trials. Reprod Toxicol. 2003;17:137–152
  36. Ernst E. Herbal medicinal products during pregnancy: are they safe?. BJOG. 2002;109:227–235
  37. Chuang C-H, Doyle P, Wang J-D, Chang P-J, Lai J-N, Chen P-C. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Safety. 2006;29:537–548
  38. Picciano MF. Pregnancy and lactation: physiological adjustments, nutritional requirements and the role of dietary supplements. J Nutr. 2003;133:1997S–2002S
  39. Office of Dietary Supplements. Dietary supplement fact sheet: vitamin A and carotenoids. http://ods.od.nih.gov/factsheets/vitamina.aspAccessed June 1, 2008
  40. Institute of Medicine, Food and Nutrition Board. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, DC: National Academy Press; 2001;
  41. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr. 2000;71:1325S–1333S
  42. Van DE, Kulier R, Gulmezoglu AM, Villar J. Vitamin A supplementation during pregnancy. Cochrane Database Syst Rev. 2002;CD001996
  43. Mills JL, Simpson JL, Cunningham GC, Conley MR, Rhoads GG. Vitamin A and birth defects. Am J Obstet Gynecol. 1997;177:31–36
  44. Baylin A, Villamor E, Rifai N, Msamanga G, Fawzi WW. Effect of vitamin supplementation to HIV-infected pregnant women on the micronutrient status of their infants. Eur J Clin Nutr. 2005;59:960–968
  45. Fawzi WW, Msamanga GI, Spiegelman D, et al. A randomized trial of multivitamin supplements and HIV disease progression and mortality. [see comment] N Engl J Med. 2004;351:23–32
  46. Villamor E, Msamanga G, Spiegelman D, et al. Effect of multivitamin and vitamin A supplements on weight gain during pregnancy among HIV-1-infected women. Am J Clin Nutr. 2002;76:1082–1090
  47. Irlam JH, Visser ME, Rollins N, Siegfried N. Micronutrient supplementation in children and adults with HIV infection. Cochrane Database of Sys Rev. 2005;CD003650
  48. Oliveira JMd, Rondo . Evidence of the impact of vitamin A supplementation on maternal and child health. PHdC Cad Saude Publica. 2007;23:2565–2575
  49. Villar J, Merialdi M, Gulmezoglu AM, et al. Nutritional interventions during pregnancy for the prevention or treatment of maternal morbidity and preterm delivery: an overview of randomized controlled trials. J Nutr. 2003;133:1606S–1625S
  50. Okonofua F. Vitamin A supplementation during pregnancy. The World Health Organization Reproductive Health Library Geneva (Switzerland): World Health Organization; 2003;
  51. World Health Organization. Safe vitamin A dosage during pregnancy, lactation (Recommendations and report of a consultation). Geneva (Switzerland): World Health Organization; 1998;
  52. Pitkin RM. Folate and neural tube defects. Am J Clin Nutr. 2007;85:285S–288S
  53. Use of dietary supplements containing folic acid among women of childbearing age—United States, 2005. MMWR Morb Mortal Wkly Rep. 2005;54:955–958
  54. Wilson RD, Johnson JA, Wyatt P, et al. Pre-conceptional vitamin/folic acid supplementation, 2007: the use of folic acid in combination with a multivitamin supplement for the prevention of neural tube defects and other congenital anomalies. J Obstet Gynaecol Can. 2007;29:1003–1026
  55. Werler MM, Louik C, Shapiro S, Mitchell AA. Prepregnant weight in relation to risk of neural tube defects. JAMA. 1996;275:1089–1092
  56. Neuhouser ML, Beresford SA. Folic acid: are current fortification levels adequate?. Nutrition. 2001;17:868–872
  57. Institute of Medicine Food and Nutrition Board. Dietary reference intakes: thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Washington, DC: National Academy Press; 1998;
  58. Czeizel AE. Nutritional supplementation and prevention of congenital abnormalities. Curr Opin Obstet Gynecol. 1995;7:88–94
  59. Hilton JJ. A comparison of folic acid awareness and intake among young women aged 18-24 years. J Am Acad Nurse Pract. 2007;19:516–522
  60. Rinsky-Eng J, Miller L. Knowledge, use, and education regarding folic acid supplementation: continuation study of women in Colorado who had a pregnancy affected by a neural tube defect. Teratology. 2002;66(Suppl 1):S29–S31
  61. de Jong-Van den Berg LTW, Hernandez-Diaz S, Werler MM, Louik C, Mitchell AA. Trends and predictors of folic acid awareness and periconceptional use in pregnant women. [see comment] Am J Obstet Gynecol. 2005;192:121–128
  62. Mischoulon D, Raab MF. The role of folate in depression and dementia. J Clin Psychiatry. 2007;68(Suppl 10):28–33
  63. Wang X, Qin X, Demirtas H, et al. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet. 2007;369:1876–1882
  64. Czeizel AE, Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med. 1992;327:1832–1835
  65. Lumley J, Watson L, Watson M, Bower C. Periconceptional supplementation with folate and/or multivitamins for preventing neural tube defects. Cochrane Database Syst Rev. 2000;CD001056
  66. Wald NJ. Folic acid and the prevention of neural-tube defects. N Engl J Med. 2004;350:101–103
  67. American College of Obstetricians and Gynecologists (ACOG). Neural tube defects. ACOG practice bulletin 44 Washington, DC: American College of Obstetricians and Gynecologists; 2003;
  68. Folic acid for the prevention of neural tube defects. American Academy of Pediatrics. Committee on Genetics Pediatrics. 1999;104:325–327
  69. Agency for Healthcare Research and Quality. Folic acid supplementation to prevent neural tube defects. US Preventive Services Task Force Rockville, MD: Agency for Healthcare Research and Quality; 2008;
  70. US Department of Agriculture. MyPyramid, 2005. (volume 2008) MyPyramid.govAccessed June 1, 2008
  71. Ervin RB, Wright JD, Reed-Gillette D. Prevalence of leading types of dietary supplements used in the Third National Health and Nutrition Examination Survey, 1988-94. Adv Data. 2004;1–7
  72. National Health and Nutrition Examination Survey. NHANES 1999-2000, 2001-2002. Atlanta (GA): National Health and Nutrition Examination Survey, Centers for Disease Control and Prevention.
  73. Willett WC, Stampfer MJ. Clinical practice (What vitamins should I be taking, doctor?). N Engl J Med. 2001;345:1819–1824
  74. Goh YI, Bollano E, Einarson TR, Koren G. Prenatal multivitamin supplementation and rates of congenital anomalies: a meta-analysis. J Obstet Gynaecol Can. 2006;28:680–689
  75. Botto LD, Mulinare J, Erickson JD. Occurrence of omphalocele in relation to maternal multivitamin use: a population-based study. Pediatrics. 2002;109:904–908
  76. Mills JL, Druschel CM, Pangilinan F, et al. Folate-related genes and omphalocele. Am J Med Genet A. 2005;136:8–11
  77. Lammer EJ, Shaw GM, Iovannisci DM, Finnell RH. Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth Defects Res A Clin Mol Teratol. 2004;70:846–852
  78. Czeizel AE, Puho E. Maternal use of nutritional supplements during the first month of pregnancy and decreased risk of Down's syndrome: case-control study. Nutrition. 2005;21:698–704discussion 704
  79. Czeizel AE, Dobo M, Vargha P. Hungarian cohort-controlled trial of periconceptional multivitamin supplementation shows a reduction in certain congenital abnormalities. Birth Defects Res A Clin Mol Teratol. 2004;70:853–861
  80. Itikala PR, Watkins ML, Mulinare J, Moore CA, Liu Y. Maternal multivitamin use and orofacial clefts in offspring. Teratology. 2001;63:79–86
  81. Allen LH. Multiple micronutrients in pregnancy and lactation: an overview. Am J Clin Nutr. 2005;81(Suppl):1206S–1212S(67 references)
  82. Ward LM, Gaboury I, Ladhani M, Zlotkin S. Vitamin D-deficiency rickets among children in Canada. CMAJ. 2007;177:161–166
  83. McCullough ML. Vitamin D deficiency in pregnancy: bringing the issues to light. J Nutr. 2007;137:305–306
  84. Dawodu A, Wagner CL. Mother-child vitamin D deficiency: an international perspective. Arch Dis Child. 2007;92:737–740
  85. Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr. 2007;137:447–452
  86. Thacher TD, Fischer PR, Strand MA, Pettifor JM. Nutritional rickets around the world: causes and future directions. Ann Trop Paediatr. 2006;26:1–16
  87. Dijkstra SH, van Beek A, Janssen JW, de Vleeschouwer LH, Huysman WA, van den Akker EL. High prevalence of vitamin D deficiency in newborn infants of high-risk mothers. Arch Dis Child. 2007;92:750–753
  88. Williams AF. Vitamin D in pregnancy: an old problem still to be solved?. Arch Dis Child. 2007;92:740–741
  89. Pawley N, Bishop NJ. Prenatal and infant predictors of bone health: the influence of vitamin D. Am J Clin Nutr. 2004;80:1748S–1751S
  90. Gale CR, Robinson SM, Harvey NC, et al. Maternal vitamin D status during pregnancy and child outcomes. Eur J Clin Nutr. 2008;62:68–77
  91. Vieth R, Bischoff-Ferrari H, Boucher BJ, et al. The urgent need to recommend an intake of vitamin D that is effective. Am J Clin Nutr. 2007;85:649–650
  92. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266–281
  93. Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;81:353–373
  94. Kovacs C. Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies. Am J Clin Nutr. 2008;88:520S–528S
  95. Specker B. Vitamin D requirements during pregnancy. Am J Clin Nutr. 2004;80:1740S–1747S
  96. American College of Obstetricians and Gynecologists. Osteoporosis. The ACOG Practice Bulletin 50 Washington, DC: American College of Obstetricians and Gynecologists; 2004;
  97. Ma J, Johns RA, Stafford RS. Americans are not meeting current calcium recommendations. Am J Clin Nutr. 2007;85:1361–1366
  98. Harville EW, Schramm M, Watt-Morse M, Chantala K, Anderson JJ, Hertz-Picciotto I. Calcium intake during pregnancy among white and African-American pregnant women in the United States. J Am Coll Nutr. 2004;23:43–50
  99. Frank E, Cone K. Characteristics of pregnant vs. non-pregnant women physicians: findings from the women physicians' health study. Int J Gynaecol Obstet. 2000;69:37–46
  100. Thomas M, Weisman SM. Calcium supplementation during pregnancy and lactation: effects on the mother and the fetus. Am J Obstet Gynecol. 2006;194:937–945
  101. Bergel E, Barros AJ. Effect of maternal calcium intake during pregnancy on children's blood pressure: a systematic review of the literature. BMC Pediatr. 2007;7:15
  102. Kalkwarf HJ, Specker BL. Bone mineral changes during pregnancy and lactation. Endocrine. 2002;17:49–53
  103. Bass JK, Chan GM. Calcium nutrition and metabolism during infancy. Nutrition. 2006;22:1057–1066
  104. O'Brien KO, Donangelo CM, Zapata CL, Abrams SA, Spencer EM, King JC. Bone calcium turnover during pregnancy and lactation in women with low calcium diets is associated with calcium intake and circulating insulin-like growth factor 1 concentrations. Am J Clin Nutr. 2006;83:317–323
  105. Weisman SM. The calcium connection to bone health across a woman's lifespan: a roundtable. J Reprod Med. 2005;50:879–884
  106. Kovacs CS. Calcium and bone metabolism during pregnancy and lactation. J Mammary Gland Biol Neoplasia. 2005;10:105–118
  107. Hofmeyr GJ, Atallah AN, Duley L. Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems [systematic review]. Cochrane Database Syst Rev. 2006;Issue 3 Art No CD001059. Accessed June 1, 2008
  108. Institute of Medicine. DRI dietary reference intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride. Washington, DC: National Academy Press; 1997;
  109. Looker AC. Iron deficiency—United States, 1999-2000. MMWR. 2002;51:897–899
  110. American College of Obstetricians and Gynecologists. ACOG practice bulletin no. 95: anemia in pregnancy. Obstet Gynecol. 2008;112:201–207
  111. Milman N, Bergholt T, Byg KE, Eriksen L, Graudal N. Iron status and iron balance during pregnancy (A critical reappraisal of iron supplementation). Acta Obstet Gynecol Scand. 1999;78:749–757
  112. Schumann K, Ettle T, Szegner B, Elsenhans B, Solomons NW. On risks and benefits of iron supplementation recommendations for iron intake revisited. J Trace Elem Med Biol. 2007;21:147–168
  113. Centers for Disease Control and Prevention. Recommendations to prevent and control iron deficiency in the United States. MMWR. 1998;47(RR-3):1–36
  114. Mahomed K. Iron supplementation in pregnancy. Cochrane Database Syst Rev. 2000;CD000117
  115. Cuervo LG, Mahomed K. Treatments for iron deficiency anaemia in pregnancy. Cochrane Database Syst Rev. 2001;CD003094
  116. Ronnenberg AG, Wood RJ, Wang X, et al. Preconception hemoglobin and ferritin concentrations are associated with pregnancy outcome in a prospective cohort of Chinese women. J Nutr. 2004;134:2586–2591
  117. Siega-Riz AM, Hartzema AG, Turnbull C, Thorp J, McDonald T, Cogswell ME. The effects of prophylactic iron given in prenatal supplements on iron status and birth outcomes: a randomized controlled trial. Am J Obstet Gynecol. 2006;194:512–519
  118. Cogswell ME, Parvanta I, Ickes L, Yip R, Brittenham GM. Iron supplementation during pregnancy, anemia, and birth weight: a randomized controlled trial. Am J Clin Nutr. 2003;78:773–781
  119. O'Donnell E, Vereker E, Lynch MA. Age-related impairment in LTP is accompanied by enhanced activity of stress-activated protein kinases: analysis of underlying mechanisms. Eur J Neurosci. 2000;12:345–352
  120. Schirer S. Causes and diagnosis of anemia due to iron deficiency. In:  Basoul DS editors. Up to Date. 2008;Waltham, MA: Up to Date
  121. Vidailhet M. Omega 3: is there a situation of deficiency in young children?. Arch Pediatr. 2007;14:116–123
  122. Crawford MA. The role of essential fatty acids in neural development: implications for perinatal nutrition. Am J Clin Nutr. 1993;57:703S–709Sdiscussion 709S-10S
  123. Food and Drug Administration. What you need to know about mercury in fish and shellfish. www.csfsan.fda.gov/∼dms/admehg3.htmlAccessed June 1, 2008
  124. Dunstan JA, Simmer K, Dixon G, Prescott SL. Cognitive assessment of children at age 2½ years after maternal fish oil supplementation in pregnancy: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2008;93:F45–F50
  125. Krauss-Etschmann S, Shadid R, Campoy C, et al. Effects of fish-oil and folate supplementation of pregnant women on maternal and fetal plasma concentrations of docosahexaenoic acid and eicosapentaenoic acid: a European randomized multicenter trial. Am J Clin Nutr. 2007;85:1392–1400
  126. Hibbeln JR, Davis JM, Steer C, et al. Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study. [see comment] Lancet. 2007;369:578–585
  127. Cohen JT, Bellinger DC, Connor WE, Shaywitz BA. A quantitative analysis of prenatal intake of n-3 polyunsaturated fatty acids and cognitive development. Am J Prev Med. 2005;29:366–374
  128. Lewin GA, Schachter HM, Yuen D, et al. Effects of omega-3 fatty acids on child and maternal health. APN, ed. 05-E025-2. Rockville, MD: Agency for Healthcare Research and Quality; 2005;
  129. Bull J, Mulvihill C, Quigley R. Prevention of low birth weight: assessing the effectiveness of smoking cessation and nutritional interventions (Evidence briefing). Agency HD; 2003;
  130. Olsen SF, Secher NJ. Low consumption of seafood in early pregnancy as a risk factor for preterm delivery: prospective cohort study. BMJ. 2002;324:447
  131. Szajewska H, Horvath A, Koletzko B. Effect of n-3 long-chain polyunsaturated fatty acid supplementation of women with low-risk pregnancies on pregnancy outcomes and growth measures at birth: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2006;83:1337–1344
  132. Makrides M, Gibson RA. Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation. Am J Clin Nutr. 2000;71:307S–311S
  133. Makrides M, Duley L, Olsen SF. Marine oil, and other prostaglandin precursor, supplementation for pregnancy uncomplicated by pre-eclampsia or intrauterine growth restriction. Cochrane Database Syst Rev. 2006;3:CD003402
  134. Institute of Medicine. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Washington, DC: National Academy Press; 2002;
  135. Simopoulos AP, Leaf A, Salem N. Workshop statement on the essentiality of and recommended dietary intakes for omega-6 and omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids. 2000;63:119–121
  136. Koletzko B, Cetin I, Brenna JT, et al. Dietary fat intakes for pregnant and lactating women. Br J Nutr. 2007;98:873–877
  137. Andersson M, Takkouche B, Egli I, Allen HE, de Benoist B. Current global iodine status and progress over the last decade towards the elimination of iodine deficiency. Bull World Health Organ. 2005;83:518–525
  138. Vitti P. Iodine deficiency disorders. UpToDate. 2008;15:
  139. Institute of Medicine. Dietary reference intake. Food and Nutrition Board Washington, DC: National Academy Press; 2001;
  140. World Health Organization. Assessment of iodine deficiency disorders and monitoring their elimination. Geneva (Switzerland): World Health Organization; 2001;
  141. Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. The epidemiology of obesity. Gastroenterology. 2007;132:2087–2102
  142. Institute of Medicine. Influence of pregnancy weight on maternal child health: a workshop report. Washington, DC: National Academy Press; 2007;
  143. Sarwer DB, Allison KC, Gibbons LM, Markowitz JT, Nelson DB. Pregnancy and obesity: a review and agenda for future research. J Womens Health (Larchmt). 2006;15:720–733
  144. McTigue KM, Harris R, Hemphill B, et al. Screening and interventions for obesity in adults: summary of the evidence for the US Preventive Services Task Force. Ann Intern Med. 2003;139:933–949
  145. Dixit A, Girling JC. Obesity and pregnancy. J Obstet Gynaecol. 2008;28:14–23
  146. Gilberto K, Benício M, Velásquez-Meléndez G. Gestational weight gain and prepregnancy weight influence postpartum weight retention in a cohort of Brazilian women. J Nutr. 2004;134:661–666
  147. American College of Obstetricians and Gynecologists. The role of the obstetrician-gynecologists in the assessment and management of obesity. No.319 Washington, DC: American College of Obstetricians and Gynecologists; 2005;
  148. Guelinckx I, Devlieger R, Beckers K, Vansant G. Maternal obesity: pregnancy complications, gestational weight gain and nutrition. Obes Rev. 2008;9:140–150
  149. Vejux N, Campan P, Agostini A. Pregnancy after gastric banding: maternal tolerance, obstetrical and neonatal outcomes. Gynecol Obstetr Fertil. 2007;35:1143–1147
  150. Jasaitis Y, Sergent F, Bridoux V, Paquet M, Marpeau L, Teniere P. Management of pregnancies after adjustable gastric banding. J Gynecol Obstetr Biol Reprod. 2007;36:764–769
  151. Ducarme G, Revaux A, Rodrigues A, Aissaoui F, Pharisien I, Uzan M. Obstetric outcome following laparoscopic adjustable gastric banding. Int J Gynaecol Obstet. 2007;98:244–247
  152. Bienstman-Pailleux J, Gaucherand P. Laparoscopic adjustable gastric banding and pregnancy. J Gynecol Obstet Biol Reprod. 2007;36:770–776
  153. Sheiner E, Menes TS, Silverberg D, et al. Pregnancy outcome of patients with gestational diabetes mellitus following bariatric surgery. Am J Obstet Gynecol. 2006;194:431–435
  154. Bar-Zohar D, Azem F, Klausner J, Abu-Abeid S. Pregnancy after laparoscopic adjustable gastric banding: perinatal outcome is favorable also for women with relatively high gestational weight gain. Surg Endosc. 2006;20:1580–1583
  155. Dixon JB, Dixon ME, O'Brien PE. Birth outcomes in obese women after laparoscopic adjustable gastric banding. Obstet Gynecol. 2005;106:965–972
  156. Williamson C. Maternal nutrition guidance: keeping the proportions. RCM Midwives. 2006;9:346–349
  157. Flegal KM, Graubard BI, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005;293:1861–1867
  158. Begum F, Buckshe K, Pande JN. Risk factors associated with preterm labour. Bangladesh Med Res Counc Bull. 2003;29:59–66
  159. Borkowski W, Mielniczuk H. The influence of social and health factors including pregnancy weight gain rate and pre-pregnancy body mass on low birth weight of the infant. Ginekol Pol. 2008;79:415–421
  160. Dietz PM, Callaghan WM, Cogswell ME, Morrow B, Ferre C, Schieve LA. Combined effects of prepregnancy body mass index and weight gain during pregnancy on the risk of preterm delivery. Epidemiology. 2006;17:170–177
  161. Lam PK, Torfs CP, Brand RJ. A low pregnancy body mass index is a risk factor for an offspring with gastroschisis. Epidemiology. 1999;10:717–721
  162. Mitchell AM, Bulik CM. Eating disorders and women's health: an update. J Midwifery Womens Health. 2006;51:193–201
  163. Franko DL, Spurrell EB. Detection and management of eating disorders during pregnancy. Obstet Gynecol. 2000;95:942–946
  164. James DC. Eating disorders, fertility, and pregnancy: relationships and complications. J Perinat Neonatal Nurs. 2001;15:36–48quiz 2 p following 82

 Conflict of Interest: Paula M. Gardiner, MD, MPH; Lauren Nelson; Cynthia S. Shellhaas, MD, MPH; Anne L. Dunlop, MD; Richard Long, MD; Sara Andrist, MPH, RD, LD; and Brian W. Jack, MD have no conflict of interest including grants, honoraria, advisory board membership, or share holdings.

PII: S0002-9378(08)02076-0

doi: 10.1016/j.ajog.2008.10.049

American Journal of Obstetrics & Gynecology
Volume 199, Issue 6, Supplement B , Pages S345-S356 , December 2008