American Journal of Obstetrics & Gynecology
Volume 200, Issue 2 , Pages 151.e1-151.e9 , February 2009

Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study

Presented in part at the 27th Annual Meeting of the Society for Maternal–Fetal Medicine, San Francisco, CA, Feb. 6-9, 2007, and in part at the 21st Congress of the International Society on Thrombosis and Hemostasis, Geneva, Switzerland, July 8-12, 2007.

  • Susan R. Kahn, MD, MSc

      Affiliations

    • Department of Medicine, McGill University Faculty of Medicine, Montreal, QC, Canada
    • Corresponding Author InformationReprints: Susan R. Kahn, MD, MSc, Center for Clinical Epidemiology and Community Studies, Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Ste. Catherine, Rm. A-127, Montreal, Quebec, Canada H3T 1E2
    • ,
  • Robert Platt, PhD

      Affiliations

    • Department of Epidemiology and Biostatistics, McGill University Faculty of Medicine, Montreal, QC, Canada
    • Department of Pediatrics, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Helen McNamara, MD, MSc

      Affiliations

    • Department of Obstetrics and Gynecology, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Rima Rozen, MD, PhD

      Affiliations

    • Department of Pediatrics, McGill University Faculty of Medicine, Montreal, QC, Canada
    • Department of Human Genetics, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Moy Fong Chen, MD

      Affiliations

    • Department of Pathology, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Jacques Genest Jr, MD

      Affiliations

    • Department of Medicine, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Lise Goulet, MD, PhD

      Affiliations

    • Département de médecine sociale et préventive, Faculté de médecine, Université de Montréal, Montreal, QC, Canada
    • Groupe de recherche interdisciplinaire en santé, Université de Montréal, Montreal, QC, Canada
    • ,
  • John Lydon, PhD

      Affiliations

    • Department of Psychology, McGill University, Montreal, QC, Canada
    • ,
  • Louise Seguin, MD, MPH

      Affiliations

    • Département de médecine sociale et préventive, Faculté de médecine, Université de Montréal, Montreal, QC, Canada
    • ,
  • Clement Dassa, PhD

      Affiliations

    • Département de médecine sociale et préventive, Faculté de médecine, Université de Montréal, Montreal, QC, Canada
    • ,
  • André Masse, MD

      Affiliations

    • Département d'Obstetrique et gynécologie, Université de Montréal, Montreal, QC, Canada
    • ,
  • Guylaine Asselin, MD

      Affiliations

    • Département d'Obstetrique et gynécologie, Université de Montréal, Montreal, QC, Canada
    • ,
  • Alice Benjamin, MD

      Affiliations

    • Department of Obstetrics and Gynecology, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Louise Miner, MD

      Affiliations

    • Department of Obstetrics and Gynecology, McGill University Faculty of Medicine, Montreal, QC, Canada
    • ,
  • Antoinette Ghanem, RN, MSc

      Affiliations

    • Groupe de recherche interdisciplinaire en santé, Université de Montréal, Montreal, QC, Canada
    • ,
  • Michael S. Kramer, MD

      Affiliations

    • Department of Epidemiology and Biostatistics, McGill University Faculty of Medicine, Montreal, QC, Canada
    • Department of Pediatrics, McGill University Faculty of Medicine, Montreal, QC, Canada

Received 18 April 2008 ,Revised 25 July 2008 ,Accepted 22 September 2008.

  • Image Result

    Study flow diagram

    Data on reasons for ineligibility were available in sample of 952 women. Most frequent reasons were lack of fluency in French or English (n = 321), plans to deliver in nonstudy hospi

    Study flow diagram

    Data on reasons for ineligibility were available in sample of 952 women. Most frequent reasons were lack of fluency in French or English (n = 321), plans to deliver in nonstudy hospital (n = 272), severe chronic disease (eg, epilepsy, Crohn's disease, multiple sclerosis) (n = 90), gestational age at initial contact > 24 weeks (n = 62), twin pregnancy (n = 29), documented incompetent cervix (n = 16), and placenta previa (n = 13).

    Kahn. Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study. Am J Obstet Gynecol 2009.

 Cite this article as: Kahn SR, Platt R, McNamara H, et al. Inherited thrombophilia and preeclampsia within a multicenter cohort: the Montreal Preeclampsia Study. Am J Obstet Gynecol 2009;200:151.e1-151.e9.

 Supported by grants from the Canadian Institutes of Health Research (MOP36424) and the March of Dimes Birth Defects Foundation (PERI grant #20-FY04-38). Dr Kahn is a career clinical investigator (chercheur-boursier clinicien) of the Fonds de la recherche en santé du Québec. Dr Platt is a career investigator (chercheur-boursier) of the Fonds de la recherche en santé du Québec. Dr Kramer is a Senior Investigator of the Canadian Institutes of Health Research.

PII: S0002-9378(08)01082-X

doi: 10.1016/j.ajog.2008.09.023

American Journal of Obstetrics & Gynecology
Volume 200, Issue 2 , Pages 151.e1-151.e9 , February 2009

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