American Journal of Obstetrics & Gynecology
Volume 199, Issue 3 , Pages 317.e1-317.e6, September 2008

Lipopolysaccharide stimulation of trophoblasts induces corticotropin-releasing hormone expression through MyD88

Presented at the 28th annual meeting of the Society for Maternal–Fetal Medicine, Dallas, TX, Jan. 28-Feb. 2, 2008.

  • Andy Uh, BSc

      Affiliations

    • Division of Pediatric Infectious Diseases, Cedars-Sinai Medical Center, Los Angeles, CA
    • Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA
    • David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center, Los Angeles, CA
  • ,
  • Richard C. Nicholson, BSc, PhD

      Affiliations

    • Mothers and Babies Research Center, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia
  • ,
  • Gustavo V. Gonzalez, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, CA
  • ,
  • Charles F. Simmons, MD

      Affiliations

    • Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA
    • David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center, Los Angeles, CA
  • ,
  • Adrian Gombart, PhD

      Affiliations

    • David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center, Los Angeles, CA
    • Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA
  • ,
  • Roger Smith, MD, PhD

      Affiliations

    • Mothers and Babies Research Center, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia
  • ,
  • Ozlem Equils, MD

      Affiliations

    • Division of Pediatric Infectious Diseases, Cedars-Sinai Medical Center, Los Angeles, CA
    • Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA
    • David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center, Los Angeles, CA
    • Corresponding Author InformationReprints: Ozlem Equils, MD, Department of Pediatrics, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Room 4220, Los Angeles, CA 90048

Received 28 February 2008; accepted 27 June 2008.

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 Cite this article as: Uh A, Nicholson RC, Gonzalez GV, et al. Lipopolysaccharide stimulation of trophoblasts induces corticotropin-releasing hormone expression through MyD88. Am J Obstet Gynecol 2008;199:317.e1-317.e6.

 This work was supported by NIH NCRR GCRC Grant M01-RR00425 (O.E.) and March of Dimes Grant 6-FY06-329 (O.E. and R.S.).

PII: S0002-9378(08)00746-1

doi:10.1016/j.ajog.2008.06.091

American Journal of Obstetrics & Gynecology
Volume 199, Issue 3 , Pages 317.e1-317.e6, September 2008