American Journal of Obstetrics & Gynecology
Volume 198, Issue 5 , Pages 511.e1-511.e15 , May 2008

The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial

Presented at the 28th Annual Meeting of the Society for Maternal-Fetal Medicine, Dallas, TX, Jan. 28-Feb. 2, 2008.

  • James M. Nicholson, MD, MSCE

      Affiliations

    • Department of Family Medicine and Community Health, University of Pennsylvania, Philadelphia, PA
    • ,
  • Samuel Parry, MD

      Affiliations

    • Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA
    • ,
  • Aaron B. Caughey, MD PhD

      Affiliations

    • Department of Obstetrics and Gynecology, University of California, San Francisco, CA
    • ,
  • Sarah Rosen, MD

      Affiliations

    • Pennsylvania Hospital, Philadelphia, PA
    • ,
  • Allison Keen, MD

      Affiliations

    • Pennsylvania Hospital, Philadelphia, PA
    • ,
  • George A. Macones, MD, MSCE

      Affiliations

    • Department of Obstetrics and Gynecology, Washington University, St. Louis, MO.

  • Image Result

    Study group development

    The flow of subjects throughout the study is shown.

    Nicholson. The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial. Am

    Study group development

    The flow of subjects throughout the study is shown.

    Nicholson. The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial. Am J Obstet Gynecol 2008.

  • Image Result
    Kaplan-Meier survival estimates, by exposedSurvival analysis of timing of delivery by study group: the number of weeks beyond 37 weeks 0 days of gestation at the time of deliveryNicholson. The impact

    Kaplan-Meier survival estimates, by exposed

    Survival analysis of timing of delivery by study group: the number of weeks beyond 37 weeks 0 days of gestation at the time of delivery

    Nicholson. The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial. Am J Obstet Gynecol 2008.

  • Image Result
    Timing of delivery, mode of labor onset, and type of nursery admission as a function of gestational ageThe continuous nature of earlier gestational age at delivery in the exposed group, as compared wi

    Timing of delivery, mode of labor onset, and type of nursery admission as a function of gestational age

    The continuous nature of earlier gestational age at delivery in the exposed group, as compared with the nonexposed group, is shown. A, Distribution of gestational age at delivery by study group: the timing of delivery by half weeks of gestation in the 2 study groups is shown. B, Distribution of mode of labor onset by gestational age and study group: the timing of labor induction and spontaneous labor by half weeks of gestation in the 2 study groups is shown. C, Distribution of type of nursery admission by gestational age and study group: the timing of NICU admission by half weeks of gestation in the 2 study groups is shown.

    Nicholson. The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial. Am J Obstet Gynecol 2008.

 Supported by the National Institute of Child Health and Human Development of the National Institutes of Health (K23-HD-42043) and by a research grant from the First Hospital Foundation. Forest Pharmaceuticals provided dinoprostone pledgets for use at the Hospital of the University of Pennsylvania.

 Cite this article as: Nicholson JM, Parry S, Caughey AB, Rosen S, Keen A, Macones GA. The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial. Am J Obstet Gynecol 2008;198:511.e1-511.e15.

 Reprints not available from the authors.

PII: S0002-9378(08)00301-3

doi: 10.1016/j.ajog.2008.03.037

American Journal of Obstetrics & Gynecology
Volume 198, Issue 5 , Pages 511.e1-511.e15 , May 2008

Article Tools

* Image Usage & Resolution