American Journal of Obstetrics & Gynecology
Volume 199, Issue 2 , Pages 127.e1-127.e6 , August 2008

A national study of the complications of lupus in pregnancy

These data were presented as an abstract at the 70th Annual Scientific Meeting of the American College of Rheumatology, Washington, DC, Nov. 10-14, 2006.

  • Megan E.B. Clowse, MD, MPH

      Affiliations

    • Division of Rheumatology and Immunology, Department of Medicine, Duke University School of Medicine, Durham, NC
    • Corresponding Author InformationReprints: Dr Megan E. B. Clowse, Box 3535 Trent Dr., DUMC, Durham, NC 27710.
    • ,
  • Margaret Jamison, PhD

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC.
    • ,
  • Evan Myers, MD, MPH

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC.
    • ,
  • Andra H. James, MD, MPH

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC.

Received 18 June 2007 ,Revised 6 December 2007 ,Accepted 7 March 2008.

References 

  1. Clark CA, Spitzer KA, Laskin CA. Decrease in pregnancy loss rates in patients with systemic lupus erythematosus over a 40-year period. J Rheumatol. 2005;32(9):1709–1712
  2. (HCUP) HCaUP. Overview of the Nationwide Inpatient Sample (NIS) 2000. Rockville, MD: The Agency for Healthcare Research and Quality; 2002;
  3. (HCUP) HCaUP. Introduction to the Nationwide Inpatient Sample (NIS) 2002. 2004;Rockville, MD
  4. James AH, Bushnell CD, Jamison MG, Myers ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol. 2005;106(3):509–516
  5. James AH, Jamison MG, Biswas MS, Brancazio LR, Swamy GK, Myers ER. Acute myocardial infarction in pregnancy: a United States population-based study. Circulation. 2006;113(12):1564–1571
  6. James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol. 2006;194(5):1311–1315
  7. Meikle SF, Steiner CA, Zhang J, Lawrence WL. A national estimate of the elective primary cesarean delivery rate. Obstet Gynecol. 2005;105(4):751–756
  8. Kabir AA, Pridjian G, Steinmann WC, Herrera EA, Khan MM. Racial differences in cesareans: an analysis of U.S. 2001 National Inpatient Sample Data. Obstet Gynecol. 2005;105(4):710–718
  9. Bruce IN, Urowitz MB, Gladman DD, Ibanez D, Steiner G. Risk factors for coronary heart disease in women with systemic lupus erythematosus: the Toronto Risk Factor Study. Arthritis Rheum. 2003;48(11):3159–3167
  10. Johnson SR, Gladman DD, Urowitz MB, Ibanez D, Granton JT. Pulmonary hypertension in systemic lupus. Lupus. 2004;13(7):506–509
  11. Clowse ME, Magder LS, Witter F, Petri M. The impact of increased lupus activity on obstetric outcomes. Arthritis Rheum. 2005;52(2):514–521
  12. Bernatsky S, Boivin JF, Joseph L, et al. Mortality in systemic lupus erythematosus. Arthritis Rheum. 2006;54(8):2550–2557
  13. Cervera R, Khamashta MA, Font J, et al. Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients. Medicine (Baltimore). 2003;82(5):299–308
  14. Moss KE, Ioannou Y, Sultan SM, Haq I, Isenberg DA. Outcome of a cohort of 300 patients with systemic lupus erythematosus attending a dedicated clinic for over two decades. Ann Rheum Dis. 2002;61(5):409–413
  15. Jacobsen S, Petersen J, Ullman S, et al. Mortality and causes of death of 513 Danish patients with systemic lupus erythematosus. Scand J Rheumatol. 1999;28(2):75–80
  16. Ward MM, Pyun E, Studenski S. Long-term survival in systemic lupus erythematosus: patient characteristics associated with poorer outcomes. Arthritis Rheum. 1995;38(2):274–283
  17. Somers E, Magder LS, Petri M. Antiphospholipid antibodies and incidence of venous thrombosis in a cohort of patients with systemic lupus erythematosus. J Rheumatol. 2002;29(12):2531–2536
  18. Erkan D. Lupus and thrombosis. J Rheumatol. 2006;33(9):1715–1717
  19. Szalai AJ, Alarcon GS, Calvo-Alen J, et al. Systemic lupus erythematosus in a multiethnic US Cohort (LUMINA) (XXX: association between C-reactive protein (CRP) gene polymorphisms and vascular events). Rheumatology (Oxford). 2005;44(7):864–868
  20. Gladman DD, Hussain F, Ibanez D, Urowitz MB. The nature and outcome of infection in systemic lupus erythematosus. Lupus. 2002;11(4):234–239
  21. Carmona F, Font J, Cervera R, Munoz F, Cararach V, Balasch J. Obstetrical outcome of pregnancy in patients with systemic lupus erythematosus: a study of 60 cases. Eur J Obstet Gynecol Reprod Biol. 1999;83(2):137–142
  22. Wong KL, Chan FY, Lee CP. Outcome of pregnancy in patients with systemic lupus erythematosus: a prospective study. Arch Intern Med. 1991;151(2):269–273
  23. Rubbert A, Pirner K, Wildt L, Kalden JR, Manger B. Pregnancy course and complications in patients with systemic lupus erythematosus. Am J Reprod Immunol. 1992;28(3-4):205–207
  24. Clark CA, Spitzer KA, Nadler JN, Laskin CA. Preterm deliveries in women with systemic lupus erythematosus. J Rheumatol. 2003;30(10):2127–2132
  25. Petri M. Hopkins Lupus Pregnancy Center: 1987 to 1996. Rheum Dis Clin North Am. 1997;23(1):1–13

 Cite this article as: Clowse MEB, Jamison M, Myers E, et al. A national study of the complications of lupus in pregnancy. Am J Obstet Gynecol 2008;199:127.e1-127.e6.

 Drs Clowse and James are funded by NIH grant 5K12-HD-043446

PII: S0002-9378(08)00276-7

doi: 10.1016/j.ajog.2008.03.012

American Journal of Obstetrics & Gynecology
Volume 199, Issue 2 , Pages 127.e1-127.e6 , August 2008

Article Tools