American Journal of Obstetrics & Gynecology
Volume 198, Issue 3 , Pages 270.e1-270.e6, March 2008

Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization

  • Seiji Isonishi, MD, PhD

      Affiliations

    • Department of Obstetrics and Gynecology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan
    • Corresponding Author InformationReprints: Seiji Isonishi, Department of Obstetrics and Gynecology, Jikei University School of Medicine, 6-41-2 Aoto, Katsushika-ku, Tokyo 125-8506, Japan
    • ,
  • Robert L. Coleman, MD

      Affiliations

    • Department of Gynecologic Oncology, University of Texas, M. D. Anderson Cancer Center, Houston, TX.
    • ,
  • Masanori Hirama, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan
    • ,
  • Yasushi Iida, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan
    • ,
  • Satomi Kitai, MD

      Affiliations

    • Department of Radiology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan
    • ,
  • Masanori Nagase, MD

      Affiliations

    • Department of Radiology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan
    • ,
  • Kazuhiko Ochiai, MD, PhD

      Affiliations

    • Department of Obstetrics and Gynecology, Jikei University School of Medicine, Aoto Hospital, Tokyo, Japan

Received 6 February 2007; received in revised form 13 July 2007; accepted 10 September 2007. published online 12 November 2007.

Objective

The objective of the study was to describe a clinically useful factors index predicting long-term efficacy of uterine artery embolization (UAE).

Study Design

Newly diagnosed patients with uterine leiomyoma wishing to retain their uterus underwent UAE at our institution. Clinical demographics and 4 prognostic factors were recovered from the medical record. A regrowth-free interval (RFI) was calculated for all patients based on leiomyoma regrowth or recurrence of any previously reported symptoms. RFI by prognostic factor was analyzed by the Kaplan-Meier method.

Results

Forty-three patients were identified. Two prognostic factors were identified by multivariate analysis: vascularity (dichotomized as hypervascular vs hypovascular; RFI at 2 years, 80% vs 20%, P = .001) and number of nodules (solitary vs multiple; RFI at 2 years, 72% vs 25% at 2 years, P = .001)

Conclusion

UAE success may be predicted by 2 preoperative parameters. Further investigation is warranted.

Key words: embolization, leiomyoma, prognostic factor

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 Cite this article as: Isonishi S, Coleman RL, Hirama M, et al. Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization. Am J Obstet Gynecol 2008;198:270.e1-270.e6.

PII: S0002-9378(07)01125-8

doi:10.1016/j.ajog.2007.09.026

American Journal of Obstetrics & Gynecology
Volume 198, Issue 3 , Pages 270.e1-270.e6, March 2008

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