Nasal bone in screening for trisomy 21: defining hypoplasia

References 

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3. Cicero S, Avgidou K, Rembouskos G, Kagan KO, Nicolaides KH. Nasal bone in first-trimester screening for trisomy 21. Am J Obstet Gynecol. 2006;195:109–114
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4. Tran L, Carr D, Mitsumori L, Uhrich S, Shields L. Second-trimester biparietal diameter/nasal bone length ratio as an independent predictor of trisomy 21. J Ultrasound Med. 2005;24:805–810
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7. Odibo A, Sehdev H, Stamilio D, Cahill A, Dunn L, Macones G. Defining nasal bone hypoplasia in second-trimester Down syndrome screening: does the use of multiples of the median (MoM) improve screening efficacy?. Am J Obstet Gynecol. 2007;(in press).