American Journal of Obstetrics & Gynecology
Volume 198, Issue 1 , Pages 43.e1-43.e5 , January 2008

The Alabama Preterm Birth Study: Umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants

  • Robert L. Goldenberg, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA
    • ,
  • William W. Andrews, PhD, MD

      Affiliations

    • Department of Obstetrics and Gynecology, University of Alabama–Birmingham Medical School, Birmingham, AL
    • ,
  • Alice R. Goepfert, MD

      Affiliations

    • Department of Obstetrics and Gynecology, University of Alabama–Birmingham Medical School, Birmingham, AL
    • ,
  • Ona Faye-Petersen, MD

      Affiliations

    • Department of Pathology, University of Alabama–Birmingham Medical School, Birmingham, AL
    • ,
  • Suzanne P. Cliver, BS

      Affiliations

    • Department of Obstetrics and Gynecology, University of Alabama–Birmingham Medical School, Birmingham, AL
    • ,
  • Waldemar A. Carlo, MD

      Affiliations

    • Department of Pediatrics, University of Alabama–Birmingham Medical School, Birmingham, AL.
    • ,
  • John C. Hauth, MD

      Affiliations

    • Department of Obstetrics and Gynecology, University of Alabama–Birmingham Medical School, Birmingham, AL

Received 14 March 2007 ,Revised 30 May 2007 ,Accepted 23 July 2007.

References 

  1. Maher CF, Haran MV, Farrell DJ, Cave DG. Ureaplasma urealyticum chorioamnionitis. Aust N Z J Obstet Gynaecol. 1994;34:477–479
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  3. Kundsin RB, Leviton A, Allred EN, Poulin SA. Ureaplasma urealyticum infection of the placenta in pregnancies that ended prematurely. Obstet Gynecol. 1996;87:122–127
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  12. Goepfert A, Andrews W, Carlo W, et al. Umbilical cord plasma interleukin-6 concentrations in preterm infants and risk of neonatal morbidity. Am J Obstet Gynecol. 2004;191:1375–1381
  13. Andrews WW, Goldenberg RL, Faye-Petersen O, Cliver SP, Goepfert A, Hauth JC. Polymorphonuclear and mononuclear cell placental infiltration, other markers of inflammation and outcomes in preterm newborns. Am J Obstet Gynecol. 2006;195:803–808
  14. Goldenberg RL, Andrews WW, Faye-Petersen O, Goepfert A, Cliver SP, Hauth JC. The Alabama Preterm Birth Study: intrauterine infection and placental histologic findings in male and female <32 week preterm births. Am J Obstet Gynecol. 2006;195:1533–1537
  15. Goldenberg RL, Andrews WW, Faye-Petersen O, Cliver SP, Goepfert A, Hauth JC. The Alabama Preterm Birth Study: corticosteroids and newborn outcomes in 23-32 week newborns with various markers of placental infection. Am J Obstet Gynecol. 2006;195:1020–1024
  16. Goldenberg RL, Andrews WW, Faye-Petersen O, Cliver SP, Goepfert A, Hauth JC. The Alabama Preterm Birth Project: placental histology in recurrent preterm birth. Am J Obstet Gynecol. 2006;195:792–796
  17. Goldenberg RL, Faye-Petersen O, Andrews WW, Goepfert A, Cliver SP, Hauth JC. The Alabama Preterm Birth Study: diffuse decidual leukocytoclastic necrosis of the decidua basalis, a placental lesion associated with preeclampsia, indicated preterm birth, and decreased fetal growth. J Matern Fetal Med. 2007;20:391–395
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  19. Andrews WW, Hauth JC, Goldenberg RL, Gomez R, Romero R, Cassell GH. Amniotic fluid interleukin-6: correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery. Am J Obstet Gynecol. 1995;173:606–612
  20. Bendon RW, Faye-Petersen O, Pavlova Z, et al. Histologic features of chorioamnion membrane rupture: development of methodology. Pediatr Pathol Lab Med. 1997;17:27–42
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  22. Redline RW. Placental inflammation. Semin Neonatol. 2004;9:265–274
  23. Redline RW, Heller D, Keating S, Kingdom J. Placental diagnostic criteria and clinical correlation—a workshop report. Placenta. 2005;26(Suppl):S114–S117
  24. Redline RW. Severe fetal placental vascular lesions in term infants with neurologic impairment. Am J Obstet Gynecol. 2005;192:452–457
  25. Volpe JJ. Hypoxic-ischemic encephalopathy: clinical aspects. In:  Volpe JJ editors. Neurology of the newborn. Philadelphia: WB Saunders; 2001;p. 331–394
  26. Carey JC, Blackwelder WC, Nugent RP, et al. Antepartum cultures for Ureaplasma urealyticum are not useful in predicting pregnancy outcome (The Vaginal Infections and Prematurity Study Group). Am J Obstet Gynecol. 1991;164:728–733

 Cite this article as: Goldenberg RL, Andrews WW, Goepfert AR, et al. The Alabama Preterm Birth Study: Umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol 2008;198:43.e1-43.e5.Reprints not available from the authors.Funded by the NICHD PERC grant (HD 33927).

PII: S0002-9378(07)00912-X

doi: 10.1016/j.ajog.2007.07.033

American Journal of Obstetrics & Gynecology
Volume 198, Issue 1 , Pages 43.e1-43.e5 , January 2008

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