American Journal of Obstetrics & Gynecology
Volume 197, Issue 2 , Pages 162.e1-162.e6 , August 2007

Blood pressure dynamics during pregnancy and spontaneous preterm birth

  • Jun Zhang, PhD, MD

      Affiliations

    • Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD
    • ,
  • Jose Villar, MD

      Affiliations

    • Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, England, UK
    • ,
  • Wenyu Sun, MD, MS

      Affiliations

    • Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD
    • ,
  • Mario Merialdi, MD, PhD

      Affiliations

    • Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Bank Special Programme of Research, World Health Organization, Geneva, Switzerland
    • ,
  • Hany Abdel-Aleem, MD

      Affiliations

    • Department of Obstetrics and Gynaecology, Assiut University Hospital, Assiut, Egypt
    • ,
  • Matthews Mathai, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Christian Medical College, Vellore, India
    • ,
  • Mohamed Ali, PhD

      Affiliations

    • Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Bank Special Programme of Research, World Health Organization, Geneva, Switzerland
    • ,
  • Kai F. Yu, PhD

      Affiliations

    • Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD
    • ,
  • Nelly Zavaleta, MD

      Affiliations

    • Instituto de Investigación Nutricional, Lima, Peru
    • ,
  • Manorama Purwar, MD

      Affiliations

    • Department of Obstetrics and Gynaecology, Government Medical College and Hospital, Nagpur, India
    • ,
  • Nguyen Thi Nhu Ngoc, MD

      Affiliations

    • Hung Vuong Hospital, Ho Chi Minh City, Vietnam
    • ,
  • Liana Campodonico, MSc

      Affiliations

    • Centro Rosarino de Estudios Perinatales, Rosario, Argentina
    • ,
  • Sihem Landoulsi, MSc

      Affiliations

    • Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Bank Special Programme of Research, World Health Organization, Geneva, Switzerland
    • ,
  • Marshall Lindheimer, MD

      Affiliations

    • Departments of Obstetrics and Gynecology and Medicine, Pritzker School of Medicine, University of Chicago, Chicago, IL.
    • ,
  • Guillermo Carroli, MD

      Affiliations

    • Centro Rosarino de Estudios Perinatales, Rosario, Argentina

Received 25 October 2006 ,Revised 18 January 2007 ,Accepted 13 March 2007.

References 

  1. Ananth CV, Savitz DA, Luther ER, Bowes WA. Preeclampsia and preterm birth subtypes in Nova Scotia, 1986 to 1992. Am J Perinatol. 1997;14:17–23
  2. Villar J, Abalos E, Carroli G, et al. Heterogeneity of perinatal outcomes in the preterm delivery syndrome. Obstet Gynecol. 2004;104:78–87
  3. Goldenberg RL. The management of preterm labor. Obstet Gynecol. 2002;100:1020–1037
  4. Villar J, Abdel-Aleen H, Merialdi M, et al. World Health Organization randomized trial of calcium supplementation among low calcium intake pregnant women. Am J Obstet Gynecol. 2006;194:639–649
  5. Villar J, Say L, Shennan A, et al. Methodological and technical issues related to the prediction, diagnostic and treatment of preeclampsia and eclampsia. Int J Obstet Gynecol. 2004;85:S28–S41
  6. Villar J, Carroli G, Wojdyla D, et al. Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions?. Am J Obstet Gynecol. 2006;194:921–931
  7. Roberts JM. Pregnancy-related hypertension. In:  Creasy RK,  Resnk R,  Iams JD editor. Maternal-fetal medicine: principles and practice. 5th ed.. Philadelphia (PA): Saunders; 2004;p. 859–893
  8. Tekay A, Campbell S. Doppler ultrasonography in obstetrics. In:  Callen PW editors. Ultrasonography in obstetrics and gynecology. 4th ed.. Philadelphia (PA): Saunders; 2000;p. 677–689
  9. Aardema MW, Saro MCS, Lander M, de Wolf BTHM, Oosterhof H, Aarnoudse JG. Second trimester Doppler ultrasound screening of the uterine arteries differentiates between subsequent normal and poor outcomes of hypertensive pregnancy: two different pathophysiological entities?. Clin Sci. 2004;106:377–382
  10. El-Hamedi A, Shillito J, Simpson NA, Walker JJ. A prospective analysis of the role of uterine artery Doppler waveform notching in the assessment of at-risk pregnancies. Hypertens Pregnancy. 2005;24:137–145
  11. Olofsson P, Laurini RN, Marsal K. A high uterine artery pulsatility index reflects a defective development of placental bed spiral arteries in pregnancies complicated by hypertension and fetal growth retardation. Eur J Obstet Gynecol Reprod Biol. 1993;49:161–168
  12. Kim YM, Bujold E, Chaiworapongsa T, et al. Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes. Am J Obstet Gynecol. 2003;189:1063–1069
  13. Naeye RL. Pregnancy hypertension, placental evidences of low uteroplacental blood flow, and spontaneous premature delivery. Hum Pathol. 1989;20:441–444
  14. Salafia CM, Ghidini A, Lopez-Zeno JA, Pezzullo JC. Uteroplacental pathology and maternal arterial mean blood pressure in spontaneous prematurity. J Soc Gynecol Investig. 1998;5:68–71
  15. Taylor RN, Roberts JM. Endothelial cell dysfunction. In:  Lindheimer MD,  Roberts JM,  Cunningham FG editor. Chesley’s hypertensive disorders in pregnancy. 2nd ed.. Stamford (CT): Appleton & Lange; 1999;p. 395–429
  16. Maltaris T, Scalera F, Schlembach D, et al. Increased uterine arterial pressure and contractility of perfused swine uterus after treatment with serum from preeclamptic women and endothelin-1. Clin Sci. 2005;109:209–215
  17. Maul H, Longo M, Saade GR, Garfield RE. Nitric oxide and its role during pregnancy: from ovulation to delivery. Curr Pharmaceutical Design. 2003;9:359–380
  18. Wilhelmsson L, Wikland M, Wiqvist N. PGH2, TxA2 and PGI2 have potent and differentiated actions on human uterine contractility. Prostaglandins. 1981;21:277–286
  19. Cobo E. Uterine hypercontractility in toxemia of pregnancy (I. Its prolonged therapeutic control). Am J Obstet Gynecol. 1964;90:505–510
  20. Zhang J, Klebanoff MA, Roberts JM. Prediction of adverse outcomes by common definitions of hypertension in pregnancy. Obstet Gynecol. 2001;97:261–267

 Reprints not available from the authors.

 This work was supported in part by the National Institutes of Health Intramural Research Program (to J.Z., W.S., and K.F.Y.).

 Cite this article as: Zhang J, Villar J, Sun W, et al. Blood pressure dynamics during pregnancy and spontaneous preterm birth. Am J Obstet Gynecol 2007;197:162.e1-162.e6.

PII: S0002-9378(07)00419-X

doi: 10.1016/j.ajog.2007.03.053

American Journal of Obstetrics & Gynecology
Volume 197, Issue 2 , Pages 162.e1-162.e6 , August 2007

Article Tools

* Image Usage & Resolution