American Journal of Obstetrics & Gynecology
Volume 196, Issue 4 , Pages 410.e1-410.e7 , April 2007

Predicting gestational diabetes: choosing the optimal early serum marker

Presented at the Twenty-fifth Annual Meeting of the American Gynecological and Obstetrical Society, Sept. 14-16, Williamsburg, VA.

  • Karen V. Smirnakis, MD, PhD, MPH

      Affiliations

    • Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    • ,
  • Alicia Plati, MPH

      Affiliations

    • Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
    • ,
  • Myles Wolf, MS, MMSc

      Affiliations

    • Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    • ,
  • Ravi Thadhani, MD, MPH

      Affiliations

    • Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    • Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
    • ,
  • Jeffrey L. Ecker, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Received 14 November 2006 ,Accepted 11 December 2006.

References 

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  3. American College of Obstetricians and Gynecologists. Gestational diabetes. Washington (DC): ACOG; 2001;ACOG Practice Bulletin Number 30
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  10. Thadhani R, Wolf M, Hsu-Blatman K, Sandler L, Nathan D, Ecker JL. First-trimester sex hormone binding globulin and subsequent gestational diabetes. Am J Obstet Gynecol. 2003;189:171–176
  11. Wolf M, Sandler L, Hsu K, Vossen-Smirnakis K, Ecker JL, Thadhani R. First-trimester C-reactive protein and subsequent gestational diabetes. Diabetes Care. 2003;26:819–824
  12. Smirnakis KV, Martinez A, Blatman KH, Wolf M, Ecker JL, Thadhani R. Early pregnancy insulin resistance and subsequent gestational diabetes mellitus. Diabetes Care. 2005;28:1207–1208
  13. Wolf M, Sandler L, Munoz K, Hsu K, Ecker J, Thadhani R. Insulin resistance and preeclampsia: a prospective study. J Clin Endocrin Metab. 2002;87:1563–1568
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  18. Knowler WC, Barrett-Connor E, Fowler SE, et al. Diabetes Prevention Program Research Group Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393–403
    Discussion
  1. Miller HC. The effect of diabetic and prediabetic pregnancies on the fetus and newborn infant. J Pediatrics. 1946;26:455–461
  2. Crowther CA, Hiller JE, Moss JR, et al. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med. 2005;352:2477–2486
  3. Berkowitz GS, Roman SH, Lapinski RH, Alvarez M. Maternal characteristics, neonatal outcome, and the time of diagnosis of gestational diabetes. Am J Obstet Gynecol. 1992;167:976–982
  4. Bartha JL, Martinez-Del-Fresno P, Comino-Delgado R. Gestational diabetes mellitus diagnosed during early pregnancy. Am J Obstet Gynecol. 2000;182:346–350
  5. Kjos SL, Buchanan TA, Greenspoon JS, et al. Gestational diabetes mellitus: the prevalence of glucose intolerance and diabetes mellitus in the first two months post partum. Am J Obstet Gynecol. 1990;163:93–98
  6. Wolf M, Sandler L, Hsu K, et al. First-trimester C-reactive protein and subsequent gestational diabetes. Diabetes Care. 2003;26:819–824
  7. Thadhani R, Wolf M, Hsu-Blatman K, et al. : First-trimester sex hormone binding globulin and subsequent gestational diabetes mellitus. Am J Obstet Gynecol. 2003;189:171–176
  8. Smirkanis KV, Martinez A, Blatman KH. Early pregnancy insulin resistance and subsequent gestational diabetes mellitus. Diabetes Care. 2005;28:1207–1208
    Discussion
  1. Wolf M, Sandler , Munoz L, Ecker K, Thadhani R. Insulin resistance and preeclampsia: A prospective study. J Clin Endocrin Metab. 2002;87:1563–1568

 Reprints not available from the authorsThis study was supported by Clinical Investigator Awards from the American Diabetes Association (to J.L.E., R.T.)Cite this article as: Smirnakis KV, Plati A, Wolf M, et al. Predicting gestational diabetes: choosing the optimal early serum marker. Am J Obstet Gynecol 2007;196:410.e1-410.e7.

PII: S0002-9378(06)02428-8

doi: 10.1016/j.ajog.2006.12.011

American Journal of Obstetrics & Gynecology
Volume 196, Issue 4 , Pages 410.e1-410.e7 , April 2007

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