American Journal of Obstetrics & Gynecology
Volume 194, Issue 5 , Pages 1423-1426, May 2006

Microscopic hematuria as a predictive factor for detecting bladder cancer at cystoscopy in women with irritative voiding symptoms

Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC

Received 24 June 2005; received in revised form 27 October 2005; accepted 13 January 2006. published online 05 April 2006.

Objective

The purpose of this study was to assess microscopic hematuria as a predictive factor for detecting bladder cancer at cystoscopy in women with irritative voiding symptoms.

Study design

We conducted a retrospective cohort analysis of women with irritative voiding symptoms who presented for urodynamic testing and cystoscopy. Irritative voiding symptoms were defined as urgency, urge incontinence, frequency, dysuria, and/or nocturia. Patient demographics, risk factors for bladder cancer, presence of microscopic hematuria, urodynamic findings, and cystoscopy and biopsy results were recorded.

Results

Of 735 patients with irritative voiding symptoms, 264 (35.9%) had microscopic hematuria and 471 (64.1%) had no hematuria. Bladder cancer was detected in 3 women, for an overall detection rate of 0.4%. Microscopic hematuria, urgency, frequency, dysuria, nocturia, age, and tobacco use were not significantly associated with bladder cancer.

Conclusion

In this cohort of women with irritative voiding symptoms, microscopic hematuria was not predictive for bladder cancer.

Key words: Microscopic hematuria, Irritative voiding symptoms, Bladder cancer, Cystoscopy

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 Presented at the Twenty-Sixth Annual Meeting of the American Urogynecologic Society, Atlanta, GA, September 15-17, 2005.Reprints not available from the authors.

PII: S0002-9378(06)00094-9

doi:10.1016/j.ajog.2006.01.053

American Journal of Obstetrics & Gynecology
Volume 194, Issue 5 , Pages 1423-1426, May 2006