American Journal of Obstetrics & Gynecology
Volume 194, Issue 5 , Pages 1404-1410 , May 2006

Skeletal muscle heavy-chain polypeptide 3 and myosin binding protein H in the pubococcygeus muscle in patients with and without pelvic organ prolapse

  • Andrew F. Hundley, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Andrew F. Hundley, MD, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Means Hall, Ohio State University, Columbus, OH 43210.
  • ,
  • Lingwen Yuan, PhD
  • ,
  • Anthony G. Visco, MD

Received 17 June 2005 ,Revised 27 October 2005 ,Accepted 13 January 2006.

References 

  1. Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol. 1997;89:501–506
  2. Mant J, Painter R, Vessey M. Epidemiology of genital prolapse: observations from the Oxford Family Planning Association Study. BJOG. 1997;104:579–585
  3. Davis GD. Uterine prolapse after laparoscopic uterosacral transection in nulliparous airborne trainees. A report of three cases. J Reprod Med. 1996;41:279–282
  4. Meeks GR, Washburne JF, McGehee RP, Wiser WL. Repair of vaginal vault prolapse by suspension of the vagina to iliococcygeus (prespinous) fascia. Am J Obstet Gynecol. 1994;171:1444–1452discussion 1452-4
  5. Harris RL, Cundiff GW, Coates KW, Bump RC. Urinary incontinence and pelvic organ prolapse in nulliparous women. Obstet Gynecol. 1998;92:951–954
  6. Benson JT, Lucente V, McClellan E. Vaginal versus abdominal reconstructive surgery for the treatment of pelvic support defects: a prospective randomized study with long-term outcome evaluation. Am J Obstet Gynecol. 1996;175:1418–1421discussion 1421-2
  7. Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S. Surgical management of pelvic organ prolapse in women [Systematic Review] Cochrane Incontinence Group. Cochrane Database of Systematic Reviews. 2006;1
  8. Tranquilli AL, Garzetti GG. A new ethical and clinical dilemma in obstetric practice: cesarean section “on maternal request”. [letter; comment] Am J Obstet Gynecol. 1997;177:245–246
  9. Visco AG, Yuan L. Differential gene expression in pubococcygeus muscle from patients with pelvic organ prolapse. Am J Obstet Gynecol. 2003;189:102–112
  10. Heit M, Benson JT, Russell B, Brubaker L. Levator ani muscle in women with genitourinary prolapse: indirect assessment by muscle histopathology. Neurourol Urodyn. 1996;15:17–29
  11. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402–408
  12. Winer J, Jung CK, Shackel I, Williams PM. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem. 1999;270:41–49
  13. Schmittgen TD, Zakrajsek BA, Mills AG, Gorn V, Singer MJ, Reed MW. Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods. Anal Biochem. 2000;285:194–204
  14. Bump RC, Mattiasson A, Bo K, Brubaker LP, DeLancey JO, Klarskov P, et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol. 1996;175:10–17
  15. Templeton NS. The polymerase chain reaction. History, methods, and applications. Diagn Mol Pathol. 1992;1:58–72
  16. Higuchi R, Fockler C, Dollinger G, Watson R. Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y). 1993;11:1026–1030
  17. Heid CA, Stevens J, Livak KJ, Williams PM. Real time quantitative PCR. Genome Res. 1996;6:986–994
  18. Sharma S, Taegtmeyer H, Adrogue J, Razeghi P, Sen S, Ngumbela K, et al. Dynamic changes of gene expression in hypoxia-induced right ventricular hypertrophy. Am J Physiol Heart Circ Physiol. 2004;286:H1185–H1192
  19. Acharyya S, Ladner KJ, Nelsen LL, Damrauer J, Reiser PJ, Swoap S, et al. Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J Clin Invest. 2004;114:370–378
  20. Gilbert R, Cohen JA, Pardo S, Basu A, Fischman DA. Identification of the A-band localization domain of myosin binding proteins C and H (MyBP-C, MyBP-H) in skeletal muscle. J Cell Sci. 1999;112:69–79
  21. Vaughan KT, Weber FE, Ried T, Ward DC, Reinach FC, Fischman DA. Human myosin-binding protein H (MyBP-H): complete primary sequence, genomic organization, and chromosomal localization. Genomics. 1993;16:34–40

 Supported by National Institutes of Health grant RO1-HD-38680.

 Presented at the Twenty-Sixth Annual Meeting of the American Urogynecologic Society, Atlanta, GA, September 15-17, 2005.

PII: S0002-9378(06)00090-1

doi: 10.1016/j.ajog.2006.01.049

American Journal of Obstetrics & Gynecology
Volume 194, Issue 5 , Pages 1404-1410 , May 2006