Volume 192, Issue 1 , Pages 121-128, January 2005
Trends and predictors of folic acid awareness and periconceptional use in pregnant women
Objective
The purpose of this study was to describe recent trends in folic acid awareness and use in the periconceptional period among pregnant women in relation to maternal sociodemographic and other relevant factors.
Study design
From 1988 to 2002, 16,555 women from the Slone Epidemiology Center Birth Defects Study were interviewed about medication use before and during pregnancy (which included multivitamins and folic acid), about whether they were aware of any vitamins that might decrease the risk of birth defects, and about sociodemographic and medical factors.
Results
Awareness of folic acid benefits increased from 0 in 1988 to 50% in 1996 and thereafter. The use of folic acid in the periconceptional period increased from 15% in 1988 to 40% in the last few years. Maternal education was a strong independent predictor of both awareness and use as were ethnicity, whether the pregnancy was wanted, family income, and whether a health care provider was consulted before planning.
Conclusion
Promoting the use of folic acid supplements, particularly among these disadvantaged groups, is essential to further decrease the prevalence of neural tube defects.
Key words: Folic acid, Periconceptional use, Awareness, Pregnancy, Predictor
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Supported in part by the National Institute of Child Health and Human Development grant No. HD27697 and the National Heart Lung and Blood Institute grant No. HL50763; the National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, through a grant to the Massachusetts Center for Birth Defects Research and Prevention, Massachusetts Department of Public Health; additional support for the Slone Epidemiology Center Birth Defects Study was provided by Rhone Poulenc Rorer, Aventis, Hoechst Marion Roussel, Pfizer, and the Glaxo-Wellcome Company.
PII: S0002-9378(04)00573-3
doi:10.1016/j.ajog.2004.05.085
© 2005 Elsevier Inc. All rights reserved.
Volume 192, Issue 1 , Pages 121-128, January 2005
