American Journal of Obstetrics & Gynecology
Volume 185, Issue 5 , Pages 1028-1031 , November 2001

Role of ultrasound for Down syndrome screening in advanced maternal age

Presented at the Twenty-first Annual Meeting of the Society for Maternal-Fetal Medicine, Reno, Nev, February 5-10, 2001.

References 

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  2. Egan JFX, Benn P, Borgida AF, Rodis JF, Campbell WA, Vintzileos AM. Efficacy of screening for fetal down syndrome in the United States from 1974 to 1997. Obstet Gynecol. 2000;96:979–985
  3. Wald NJ, Cuckle HS, Densem JW, Nanchahal K, Royston P, Chard T, et al.  Maternal serum screening for Down’s syndrome in early pregnancy. BMJ. 1988;297(6653):883–887
  4. Wald NJ, Densem JW, Smith D, Klee GG. Four marker serum screening for Down’s syndrome. Prenat Diagn. 1994;14:707–716
  5. Devore GR. Trisomy 21: 91% detection rate using second-trimester ultrasound markers. Ultrasound Obstet Gynecol. 2000;16:133–141
  6. Vergani P, Locatelli A, Piccoli MG, Ceruti P, Mariani F, Pezzullo JC, et al.  Best second trimester sonographic markers for the detection of trisomy 21. J Ultrasound Med. 1999;18:469–473
  7. Verdin SM, Economides DL. The role of ultrasonographic markers for trisomy 21 in women with positive serum biochemistry. Br J Obstet Gynecol. 1998;105:63–67
  8. Wax JR, Guilbert J, Mather J, Chen C, Royer D, Steinfeld JD, et al.  Efficacy of community-based second trimester genetic sonography in detecting the chromosomally abnormal fetus. J Ultrasound Med. 2000;19:689–694
  9. Nyberg DA, Luthy DA, Resta RG, Nyberg BC, Williams MA. Ageadjusted ultrasound risk assessment for fetal Down’s syndrome during the second trimester: description of the method and analysis of 142 cases. Ultrasound Obstet Gynecol. 1998;12:8–14
  10. Haddow JE, Palomaki GE, Knight GJ, Cunningham GC, Lustig LS, Boyd PA. Reducing the need for amniocentesis in women 35 years of age or older with serum markers for screening. N Engl J Med. 1994;330:1114–1118
  11. Elias S, Simpson JL. Amniocentesis. In: 3rd ed.  Milunsky A editors. Genetic disorders and the fetus. Baltimore: : Johns Hopkins University Press; 1992;p. 33–57
  12. Yagel S, Anteby EY, Hochner-Celnikier D, Ariel I, Chaap T, Ben Neriah Z. The role of midtrimester targeted fetal organ screening combined with the “triple test” and maternal age in the diagnosis of trisomy 21: a retrospective study. Am J Obstet Gynecol. 1998;178:40–44
  13. Nadel AS, Bromley B, Frigoletto FD, Bennaceraf BR. Can the presumed risk of autosomal trisomy be decreased in fetuses of older women following a normal sonogram?. J Ultrasound Med. 1995;14:297–302
  14. Vintzileos AM, Ananth CV, Fisher AJ, Smulian JC, Day-Salvatore D, Beazoglou T, et al.  An economic evaluation of second-trimester genetic ultrasonography for prenatal detection of Down syndrome. Am J Obstet Gynecol. 1998;179(5):1214–1219
  15. Kuppermann M, Nease RF, Learman LA, Gates E, Blumberg B, Washington AE. Procedure-related miscarriages and Down syndrome-affected births: implications for prenatal testing based on women’s preferences. Obstet Gynecol. 2000;96:979–985

☆ No reprints are available.

PII: S0002-9378(01)69584-X

doi: 10.1067/mob.2001.117673

American Journal of Obstetrics & Gynecology
Volume 185, Issue 5 , Pages 1028-1031 , November 2001

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