« Previous
Next »
American Journal of Obstetrics & Gynecology
Volume 182, Issue 5
, Pages 1258-1263
, May 2000
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene as a new risk factor for placental vasculopathy
References
-
.
Disorders of transsulfuration.
In:
Scriver CR, Beaudet AL, Sly WS, Valle D editor.
The metabolic and molecular bases of inherited disease. New York: McGraw-Hill; 1995;p. 1279–1327
-
.
Plasma homocysteine and cardio-vascular disease.
In:
Francis RB editors.
Atherosclerotic cardiovascular disease, hemostasis, and endothelial function. New York: Marcel Dekker; 1992;p. 183–1136
- Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med. 1996;334:759–762
- Homocysteine metabolism in pregnancies complicated by neural tube defects. Lancet. 1995;345:149–151
-
Hyperhomocysteinemia: a risk factor in women with unexplained recurrent early pregnancy loss.
Fertil Steril. 1993;60:120–125
- Hyperhomocysteinemia: a risk factor for placental abruption or infarction. Eur J Obstet Gynecol Reprod Biol. 1996;66:23–29
- Underlying disorders associated with severe early-onset preeclampsia. Am J Obstet Gynecol. 1995;173:1042–1048
- Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. 1996;58:35–41
- A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10:111–113
- Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation. 1996;93:7–9
- Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. Lancet. 1995;346:1070–1071
- The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes. Arterioscler Thromb Vasc Biol. 1997;17:1157–1162
- . Fact and fancy: what can we really tell from the placenta?. Arch Pathol Lab Med. 1991;115:672–681
- . Placental bed biopsies in placental abruption. Br J Obstet Gynaecol. 1992;99:651–654
- . Placental thrombi and other vascular lesions: classification, morphology, and clinical correlations. Pathol Res Pract. 1993;189:2–17
- . Placental abruption and its association with hypertension and prolonged rupture of membranes: a methodological review and meta-analysis. Obstet Gynecol. 1996;88:309–318
- . Maternal age, obstetric complications, and the outcome of pregnancy. Obstet Gynecol. 1983;61:210–216
-
Three different methods for the determination of total homocysteine in plasma.
Ann Clin Biochem. 1995;32(Pt 2):218–220
- . Multivitamin supplementation in oral contraceptive users. Contraception. 1991;44:277–288
- . Effects of sub-50 oral contraceptives on homocysteine metabolism: a preliminary study. Contraception. 1992;45:129–139
- . A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215
-
Thermolabile methylenetetrahydrofolate reductase in coronary artery disease.
Circulation. 1997;96:1573–1577
- A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects. QJM. 1995;88:763–766
- . Recurrent early pregnancy loss and genetic related disturbances in folate and homocysteine metabolism. Br J Hosp Med. 1997;58:511–513
- . Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia. J Med Genet. 1997;34:525–526
- . Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet. 1991;338:131–137
☆ Supported by grants 94.029 and D97.021 from the Dutch Heart Foundation, The Hague, the Netherlands.
☆☆ Reprint requests: Henk J. Blom, PhD, Department of Paediatrics, University Hospital Nijmegen PO Box 9101, 6500 HB Nijmegen, The Netherlands.
PII: S0002-9378(00)70194-3
doi: 10.1067/mob.2000.105199
© 2000 Mosby, Inc. All rights reserved.
« Previous
Next »
American Journal of Obstetrics & Gynecology
Volume 182, Issue 5
, Pages 1258-1263
, May 2000
