American Journal of Obstetrics & Gynecology
Volume 202, Issue 1 , Pages 54.e1-54.e5 , January 2010

Hereditary thrombophilia and recurrence of ischemic placental disease

  • Eric Verspyck, MD, PhD

      Affiliations

    • Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France
    • Corresponding Author InformationReprints: Eric Verspyck, MD, Clinique Gynécologique et Obstétricale, Hôpital Charles Nicolle-CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France
    • ,
  • Jeanne-Yvonne Borg, MD

      Affiliations

    • Department of Haematology and Coagulation Disorders, Rouen University Hospital, Rouen, France
    • ,
  • Horace Roman, MD, PhD

      Affiliations

    • Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France
    • ,
  • Bernard Thobois, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Maternité Mathilde, Rouen, France
    • ,
  • Patrick Pia, MD

      Affiliations

    • Department of Obstetrics and Gynecology, Maternité Elbeuf, Elbeuf, France
    • ,
  • Loïc Marpeau, MD, PhD

      Affiliations

    • Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France

Received 21 January 2009 ,Revised 5 June 2009 ,Accepted 17 August 2009.

References 

  1. Kupferminc MJ, Eldor A, Steinman N, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med. 1999;340:9–13
  2. Kujovich JL. Thrombophilia and pregnancy complications. Am J Obstet Gynecol. 2004;191:412–424
  3. Lin J, August P. Genetic thrombophilias and preeclampsia: a meta-analysis. Obstet Gynecol. 2005;105:182–192
  4. Bates SM, Greer IA, Hirsh J, Ginsberg JS. Use of antithrombotic agents during pregnancy. Chest. 2004;126:627S–644S
  5. Sibai BM. Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol. 2003;102:181–192
  6. Duley L, Henderson-Smart DJ, Meher S, King JF. Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev. 2007;(2):CD004659
  7. Verspyck E, Le Cam-Duchez V, Goffinet F, Tron F, Marpeau L, Borg JY. Thrombophilia and immunological disorders in pregnancies as risk factors for small gestational age infants. Br J Obstet Gynaecol. 2002;109:28–33
  8. Kupferminc MJ, Fait G, Many A, et al. Low-molecular-weight heparin for the prevention of obstetric complications with thrombophilias. Hypertens Pregnancy. 2001;20:35–44
  9. Branch DW, Porter TF, Rittenhouse L, et al. Antiphospholipid antibodies in women at risk for preeclampsia. Am J Obstet Gynecol. 2001;184:825–834
  10. Van Rijn BB, Hoeks LB, Bots ML, Franx A, Bruinse HW. Outcomes of subsequent pregnancy after first pregnancy with early-onset preeclampsia. Am J Obstet Gynecol. 2006;195:723–728
  11. Ananth CV, Peltier MR, Kirby RS, Getahun D, Vintzileos AM. Recurrence of ischemic placental disease. Obstet Gynecol. 2007;110:128–133
  12. Black M, Shetty A, Bhattacharya S. Obstetric outcomes subsequent to intrauterine death in the first pregnancy. Br J Obstet Gynaecol. 2007;115:269–274
  13. Conde-Agudelo A, Villar J, Lindheimer M. World Health Organization systematic review of screening tests for preeclampsia. Obstet Gynecol. 2004;104:1367–1391
  14. Spencer K, Yu CK, Savvidou M, Papageorghiou AT, Nicolaides KH. Prediction of pre-eclampsia by uterine artery Doppler ultrasonography and maternal serum pregnancy-associated plasma protein-A, free beta-human chorionic gonadotropin, activin A and inhibine A at 22 + 0 to 24 + 6 weeks' gestation. Ultrasound Obstet Gynecol. 2006;27:658–663
  15. Mostello D, Kallogjeri D, Tungsiripat R, Leet T. Recurrent of preeclampsia: effects of gestational age at delivery of the first pregnancy, body mass index, paternity, and interval between births. Am J Obstet Gynecol. 2008;199:55–57
  16. Brown MA, Mackenzie C, Dunsmuir W, et al. Can we predict recurrence of pre-eclampsia or gestational hypertension?. Br J Obstet Gynaecol. 2007;114:984–993
  17. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: ACCP evidence-based clinical practice guidelines, 8th ed. Chest. 2008;133:844S–886S

 Cite this article as: Verspyck E, Borg J-Y, Roman H, et al. Hereditary thrombophilia and recurrence of ischemic placental disease. Am J Obstet Gynecol 2010;202:54.e1-5.

PII: S0002-9378(09)00944-2

doi: 10.1016/j.ajog.2009.08.019

American Journal of Obstetrics & Gynecology
Volume 202, Issue 1 , Pages 54.e1-54.e5 , January 2010

Article Tools