American Journal of Obstetrics & Gynecology
Volume 200, Issue 4 , Pages 392.e1-392.e10 , April 2009

Circulating angiogenic factors in gestational proteinuria without hypertension

  • Alexander M. Holston, MD

      Affiliations

    • Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD
    • Division of Epidemiology, Statistics, and Prevention Research, Department of Health and Human Services, National Institute of Child Health and Human Development, Bethesda, MD
  • ,
  • Cong Qian, MS

      Affiliations

    • Allied Technology Group, Rockville, MD
  • ,
  • Kai F. Yu, PhD

      Affiliations

    • Division of Epidemiology, Statistics, and Prevention Research, Department of Health and Human Services, National Institute of Child Health and Human Development, Bethesda, MD
  • ,
  • Franklin H. Epstein, MD

      Affiliations

    • Department of Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA
  • ,
  • S. Ananth Karumanchi, MD

      Affiliations

    • Department of Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA
    • Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA
  • ,
  • Richard J. Levine, MD

      Affiliations

    • Division of Epidemiology, Statistics, and Prevention Research, Department of Health and Human Services, National Institute of Child Health and Human Development, Bethesda, MD
    • Corresponding Author InformationReprints: Richard J. Levine, MD, Divison of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, Department of Health and Human Services, Bethesda, MD 20892

Received 27 June 2008 ,Revised 22 August 2008 ,Accepted 7 October 2008.

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 This study was supported by funds and salary from the intramural research program of the National Institutes of Health and by salary from the US Navy; by the National Institute of Child Health and Human Development under contracts N01-HD-1-3121 through 3126, N01-HD-3154, and N01-HD-5-3246, with cofunding from the National Heart, Lung, and Blood Institute (Calcium for Preeclampsia Prevention trial database and specimen repository); and by National Institutes of Health Grants DK065997 and HL079594 (S.A.K., an investigator of the Howard Hughes Medical Institute).

 The views expressed are those of the authors and do not reflect the official policy or position of the Department of Defense or the US Government.

 Dr Karumanchi reports having served as a consultant to Abbott, Beckman Coulter, Roche, and Johnson & Johnson and having been named co-inventor on multiple provisional patents that were filed by Beth Israel Deaconess Medical Center for the use of angiogenesis-related proteins for the diagnosis and treatment of preeclampsia. These patents have been nonexclusively licensed to several companies.

 Cite this article as: Holston AM, Qian C, Yu KF, Epstein FH, Karumanchi SA, Levine RJ. Circulating angiogenic factors in gestational proteinuria without hypertension. Am J Obstet Gynecol 2009;200:392.e1-392.e10.

PII: S0002-9378(08)02045-0

doi: 10.1016/j.ajog.2008.10.033

American Journal of Obstetrics & Gynecology
Volume 200, Issue 4 , Pages 392.e1-392.e10 , April 2009