American Journal of Obstetrics & Gynecology
Volume 198, Issue 1 , Pages 45.e1-45.e7 , January 2008

Folic acid supplementation in early second trimester and the risk of preeclampsia

  • Shi Wu Wen, MB, PhD

      Affiliations

    • OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    • Department of Epidemiology and Community Medicine, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • Corresponding Author InformationReprints: Shi Wu Wen, MB, PhD, OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, 501 Smyth Rd, Box 241, Ottawa, Ontario, Canada K1H 8L6
    • ,
  • Xi-Kuan Chen, MD, PhD

      Affiliations

    • OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • ,
  • Marc Rodger, MD

      Affiliations

    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • Division of Hematology, Department of Medicine, Queen’s University School of Medicine, Kingston, ON
    • ,
  • Ruth Rennicks White, RN, BScN

      Affiliations

    • OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • ,
  • Qiuying Yang, MD, PhD

      Affiliations

    • OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • ,
  • Graeme N. Smith, MD, PhD

      Affiliations

    • Queen’s Perinatal Research Unit, Kingston General Hospital, and the Department of Obstetrics and Gynecology, Queen’s University School of Medicine, Kingston, ON
    • ,
  • Ronald J. Sigal, MD, MPH

      Affiliations

    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
    • Department of Medicine, Queen’s University School of Medicine, Kingston, ON
    • Division of Endocrinology, University of Calgary, Calgary, AB, Canada.
    • ,
  • Sherry L. Perkins, PhD

      Affiliations

    • Division of Biochemistry, Queen’s University School of Medicine, Kingston, ON
    • ,
  • Mark C. Walker, MD, MSc

      Affiliations

    • OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    • Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada

Received 20 November 2006 ,Revised 17 April 2007 ,Accepted 29 June 2007.

References 

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 Cite this article as: Wen SW, Chen X-K, Rodger M, et al. Folic acid supplementation in early second trimester and the risk of preeclampsia. Am J Obstet Gynecol 2008;198:45.e1-45.e7.Supported in part by a grant from the Canadian Institute for Health Research (Grant MOP 53188). S.W.W., G.N.S., R.J.S., and M.C.W. are recipients of a New Investigators’ Award from the Canadian Institute for Health Research. M.R. is a Clinical Investigator of the Heart and Stroke Foundation of Canada, and X.-K.C. and Q.Y. are Canadian Institute for Health Research/Strategic Training Initiatives of Research in Reproductive Health Sciences postdoctor fellows.

PII: S0002-9378(07)00844-7

doi: 10.1016/j.ajog.2007.06.067

American Journal of Obstetrics & Gynecology
Volume 198, Issue 1 , Pages 45.e1-45.e7 , January 2008

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