American Journal of Obstetrics & Gynecology
Volume 197, Issue 3, Supplement , Pages S101-S106 , September 2007

Prevention of mother-to-child transmission services as a gateway to family-based human immunodeficiency virus care and treatment in resource-limited settings: rationale and international experiences

  • Elaine J. Abrams, MD

      Affiliations

    • International Center for HIV/AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY
    • Harlem Hospital Center, Columbia University, New York, NY
    • Corresponding Author InformationReprints: Elaine J. Abrams, MD, International Center for HIV/AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, 722 West 168th Street, 7th Floor, New York, NY 10032
    • ,
  • Landon Myer, PhD

      Affiliations

    • Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
    • ,
  • Allan Rosenfield, MD

      Affiliations

    • International Center for HIV/AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY
    • ,
  • Wafaa M. El-Sadr, MD, MPH

      Affiliations

    • International Center for HIV/AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY
    • Harlem Hospital Center, Columbia University, New York, NY

Received 2 February 2007 ,Accepted 15 March 2007.

References 

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  9. Shaffer N, Roongpisuthipong A, Siriwasin W, et al. Maternal virus load and perinatal human immunodeficiency virus type 1 subtype E transmission, Thailand (Bangkok Collaborative Perinatal HIV Transmission Study Group). J Infect Dis. 1999;179:590–599
  10. Mofenson L, Lambert J, Stiehm E, et al. Risk factors for perinatal transmission of human immunodeficiency virus type 1 in women treated with zidovudine (Pediatric AIDS Clinical Trials Group Study 185 Team). N Engl J Med. 1999;341:385–393
  11. Breastfeeding and HIV International Transmission Study Group. Late postnatal transmission of HIV-1 in breast-fed children: an individual patient data meta-analysis. J Infect Dis. 2004;189:2154–2166
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  13. European Collaborative Study. Mother-to-child transmission in the era of highly active antiretroviral therapy. Clin Infect Dis. 2005;40:458–465
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  15. Dabis F, Bequet L, Ekouevi DK, et al. Field efficacy of zidovudine, lamivudine and single-dose nevirapine to prevent peripartum HIV transmission. AIDS. 2005;19:309-1
  16. Western Cape Provincial Government. Revised protocol for PMTCT services in the Western Cape. Cape Town: Western Cape Provincial Government; 2004;
  17. Coetzee D, Hilderbrand K, Boulle A, Draper B, Abdullah F, Goemaere E. Effectiveness of the first district-wide programme for the prevention of mother-to-child transmission of HIV in South Africa. Bull World Health Organ. 2005;83:489–494
  18. Rabkin M, El-Sadr WM. Saving Mothers, Saving Families: The MTCT-Plus Initiative. Geneva: World Health Organization; 2003;
  19. Chi BH, Fusco H, Sinkala M, Goldenberg RL, Stringer JS. Cost and enrolment implications of targeting different source population for an HIV treatment program. J Acquir Immune Defic Syndr. 2005;40:350–355
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  21. Lawn SD, Myer L, Orrell C, Bekker LG, Wood R. Early mortality among adults accessing a community-based antiretroviral service in South Africa: implications for programme design. AIDS. 2005;19:2141–2148
  22. Lyon ME, Trexler C, Akpan-Townsend C, et al. A family group approach to increasing adherence to therapy in HIV-infected youths: results of a pilot project. AIDS Patient Care STDS. 2003;17:299–308
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  25. Myer L, Rabkin M, Abrams EJ, Rosenfield A, El-Sadr WM. Columbia University MTCT-Plus Initiative (Focus on women: linking HIV care and treatment with reproductive health services in the MTCT-Plus Initiative). Reprod Health Matters. 2005;13:136–146

 The MTCT-Plus Initiative is supported through a consortium of foundations including the Bill and Melinda Gates Foundation, William and Flora Hewlett Foundation, Robert Wood Johnson Foundation, Henry J. Kaiser Family Foundation, John D. and Catherine T. MacArthur Foundation, David and Lucile Packard Foundation, Rockefeller Foundation, and Starr Foundation, and is administered through the International Center for AIDS Care and Treatment Programs at the Mailman School of Public Health, Columbia University.

PII: S0002-9378(07)00434-6

doi: 10.1016/j.ajog.2007.03.068

American Journal of Obstetrics & Gynecology
Volume 197, Issue 3, Supplement , Pages S101-S106 , September 2007

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