American Journal of Obstetrics & Gynecology
Volume 172, Issue 2, Part 1 , Pages 700-705 , February 1995

Risk factors for mother-to-child transmission of human immunodeficiency virus-1 infection

  • Marleen Temmerman, MD, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Marleen Temmerman, MD, PhD, Department of Obstetrics and Gynaecology, University Hospital of Ghent, De Pintelaan 185, 9000 Ghent, Belgium.
    • Departments of Medical Microbiology University of Nairobi, Nairobi, Kenya
    • Institute of Tropical Medicine, Antwerp, Belgium
    • ,
  • Aggrey O. Nyong'o, MD

      Affiliations

    • Department of Human Pathology, University of Nairobi, Nairobi, Kenya
    • ,
  • Joh Bwayo, MD

      Affiliations

    • Department of Human Pathology, University of Nairobi, Nairobi, Kenya
    • ,
  • Katrien Fransen, MSc

      Affiliations

    • Institute of Tropical Medicine, Antwerp, Belgium
    • ,
  • Mieke Coppens, MD

      Affiliations

    • Department of Pathology University Hospital Ghent, Belgium
    • ,
  • Peter Piot, MD, PhD

      Affiliations

    • Institute of Tropical Medicine, Antwerp, Belgium

Received 23 February 1994 ,Revised 23 June 1994 ,Accepted 27 June 1994.

References 

  1. Dabis F, Msellati P, Dunn D, et al.  Estimating the rate of mother-to-child transmission of HIV: report of a workshop on methodological issues. Ghent (Belgium). 17–20 February 1992 AIDS. 1993;7:1139–1148
  2. Krivine A, Firtion G, Cao L, Francoual C, Henrion R, Lebon P. HIV replication during the first week of life. Lancet. 1992;339:1187–1189
  3. Temmerman M, Chomba EN, Ndinya-Achola J, Plummer FA, Coppens M, Piot P. Maternal HIV-1 infection and pregnancy outcome. Obstet Gynecol. 1994;83:495–501
  4. Rogers MF, Ou C-Y, Rayfield M, et al.  Use of the polymerase chain reaction for early detection of the proviral sequences of human immunodeficiency virus in infants born to seropositive mothers. N Engl J Med. 1989;320:1649–1654
  5. Scarlatti G, Lombardi V, Plebani A, et al.  Polymerase chain reaction, virus isolation and antigen assay in HIV-1-antibody-positive mothers and children. AIDS. 1991;5:1173–1178
  6. Van de Perre P, Simonon A, Msellati P, et al.  Postnatal transmission of human immunodeficiency virus type I from mother to infant. N Engl J Med. 1991;325:593–598
  7. Fahey JL, Taylor JMG, Detels R, et al.  The prognostic value of cellular and serological markers in infection with human immunodeficiency virus type I. N Engl J Med. 1990;322:166–172
  8. In: European collaborative study: risk factors for mother-to-child transmission of HIV-1. 4th ed.. Lancet. 339:1992;p. 1007–1012
  9. Datta P, Embree J, Plummer E, et al.  Perinatal HIV-1 transmission in Nairobi: 5 years follow-up. [Abstract MC3] In: Proceedings of the seventh international conference on AIDS. Florence, Italy, June 16–21, 1991. Florence: International Conference on AIDS; 1991;
  10. Ryder RW, Nsa W, Hassig SE, et al.  Perinatal transmission of the human immunodeficiency virus type 1 to infants of seropositive women in Zaire. N Engl J Med. 1989;320:1637–1642
  11. Bulfamante G, Muggiasca L, Conti M, et al.  Placental Morphological findings in HIV positive pregnancies: frequency and correlation of the clinical status of mothers and their babies. [Abstract WC3228] In: Proceedings of the seventh international conference on AIDS. Florence Italy, June 16–21, 1991. Florence: International Conference on AIDS; 1991;
  12. St Louis ME, Kamenga M, Brown C, et al.  Risk for perinatal transmission according to maternal immunologic, virologic and placental factors. JAMA. 1993;269:2853–2859
  13. Hitimana DG, Lepage P, Van de Perre P, et al.  Perinatal study of HIV-1 in Kigali, Rwanda: estimation of the mother-to-child transmission rate and analysis of its determinants. [Abstract POC4019] In: Proceedings of the eighth international conference on AIDS/third STD world congress. Amsterdam, The Netherlands, July 19–24, 1992. Amsterdam: International Conference on AIDS/STD World Congress; 1992;
  14. Bulterys M, Chao A, Dushimimana A, et al.  Multiple sexual partners and mother-to-child transmission of HIV-1. AIDS. 1993;7:1639–1645
  15. Gabiano C, Tovo P-A, de Martino M, et al.  Mother-to-child transmission of human immunodeficiency virus type 1: risk of infection and correlates of transmission. Pediatrics. 1992;90:369–374
  16. Scherpbier HJ, Kampinga CA, Boer K. Prognostic factors for vertical HIV transmission. [Abstract POC4231] In: Proceedings of the eighth international conference on AIDS/third STD world congress. Amsterdam, The Netherlands, July 19–24, 1992. Amsterdam: Internatioal Conference on AIDS/STD World Congress; 1992;
  17. Blanche S, Rouzioux C, Guihard Moscato M-L, et al.  A prospective study of infants born to women seropositive for human immunodeficiency virus type I. N Engl J Med. 1989;320:1634–1648
  18. Lindgren S, Anzen B, Bohlin A-B, Lindman K. HIV and child-bearing: clinical outcome and aspects of mother-to-infant transmission. AIDS. 1995;5:1111–1116
  19. Goedert JJ, Mendez H, Drummond JE, et al.  Mother-to-infant transmission of human immunodeficiency virus type 1: association with prematurity or low anti-gup 120. Lancet. 1989;2:1351–1354

☆ Supported by grants from the Science and Technology for Developing Countries (STD) programme (contract No. TS2-M-0003-B) of the Commission of the European Communities, Brussels, Belgium, and the Global Program on AIDS, World Health Organization, Geneva, Switzerland.

PII: 0002-9378(95)90597-9

American Journal of Obstetrics & Gynecology
Volume 172, Issue 2, Part 1 , Pages 700-705 , February 1995

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